Amplipen

Amplipen Injection 500mg

Ampicillin Sodium Ampicillin Base

P.D.H. PHARMACEUTICALS (PVT) LTD.

Drug Identity

Active Ingredient
Ampicillin Sodium Ampicillin Base
Drug Class
Beta-Lactam Antibacterials, Penicillins
ATC Code
J01CA01, S01AA19
Status
Essential Medicine

What is Amplipen?

Uses
Ampicillin is a penicillin antibiotic that fights bacteria. Ampicillin injection is used to treat or prevent many different types of infe...

How It Works

May be administered by direct IV push over 3-5 min at a rate not to exceed 100 mg/min or IV intermittent infusion over 15-30 min at concentration not to exceed 30 mg/ml .Add 1.2 ml of SWFI or bacteriostatic water for injection to each 125 mg vial, 1 ml of diluent to each 250 mg vial, 1.8 ml of diluent to each 500 mg vial, 3.5 ml of diluent to each 1 gm vial, or 6.8 ml of diluents to each 2 gm vial. Intermittent infusion: Add 5 ml of SWFI or bacteriostatic water for injection to each 125, 250, or 500 mg vial or 7.4 to 10 ml of diluent to each 1 or 2 gm vial.

How to Take It

1
Adult · IV,IM
500 to 1000 mg — 6 hourly
Maximum dose: 12 g
2
Adult · PO
250 to 500 mg — 6 hourly
3
Child · Intra Muscular
12.5 to 25 mg/kg — 6 hourly
-
4
Child · Intra Venous
12.5 to 25 mg/kg — 6 hourly
-
5
Child · Oral
12.5 to 25 mg/kg — 6 hourly
-

Safety Alerts

History of flucloxacillin associated jaundice/hepatic dysfunction, hypersensitivity to penicillins, cephalosporins or other beta-lactams

Important Warnings

Renal impairment, acute or chronic lymphocytic leukaemia and cytomegalovirus infection (increased risk of erythematous rashes), glandular fever, maintainadequate hydration with high doses (particularly duringparenteral therapy)
Accumulation of sodium can occurwith high parenteral IV doses, risk of crystalluria with high doses
Monitor renal, hepatic and haematological function in neonates

Side Effects

Hypersensitivity reactionGI disturbancenausea and vomiting. Rarely hepatitischolestatic jaundicehaematological and CNS effectspseudomembranous colitisincreased INRStevens-Johnsons syndrometoxic epidermal necrosis.

Drug Interactions

Anticoagulants
allopurinol
probenecid.

Pregnancy & Lactation

Pregnancy
Caution advised
Lactation
Caution advised

Storage

Inj (reconstituted soln) Store at room temperature. Use within 1 hr if kept at room temperature. Oral Susp (reconstituted soln) Store in refrigerator. Do not Freeze. Use within 2 weeks if kept at room temperature. Syrup, Caps Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.

Price Intelligence

Rs 82.77
DRAP approved maximum price · per unit · approved 04 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper unitRs 82.77

Should you consider an alternative?

Other options containing Ampicillin Sodium Ampicillin Base, and what they are not.

These contain this ingredient plus others. They are different medicines — do not swap.

Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.

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Prices as of 30 July 2026 · DRAP ceiling as of 30 July 2026 · schema v3-SKU

For medicine intelligence and professional reference only. Not medical advice.