Drug Identity
Active Ingredient
Flumazenil
Drug Class
General
What is Anexate?
Uses
Flumazenil is used to reverse the effects of a benzodiazepine (BENZ-oh-dye-AYZ-e-peen) sedative such as Valium, Versed, Xanax, Tranxene ,...
How It Works
Administered IV over 15 to 30 seconds. To minimize pain at the injection site, Flumazenil should be ad-ministered through a freely running IV infusion line into a large vein. Extravasation should be avoided.
How to Take It
1
Adult · IV
200 ug — As recommended.
Load for 15 Seconds
2
Adult · IV
300 to 600 ug — As recommended.
Maintenance, after 60 Sec interval
Safety Alerts
Life-threatening condition (e
raised intracranial pressure, status epileptic us) controlled by benzodiazepines
Important Warnings
Head injury, avoid rapid injection following major surgery or in high-risk or anxious patients, benzodiazepine dependence (may precipitate withdrawal symptoms), elderly, ensure neuromuscular blockade cleared before administering, history of panic disorders, prolonged benzodiazepine therapy for epilepsy, short-acting (repeat doses may be necessary)
Side Effects
Nauseavomitinganxietyfearpalpitationagitationchillsconvulsionsdizzinessflushingif wakening too rapidtransient increase in blood pressure and heart-rate in intensive care patientsvery rarely convulsions (particularly in epileptics).
Drug Interactions
Receiving flumazenil after taking large doses of certain antidepressants can cause dangerous or life-threatening side effects. Tell your doctor before you receive flumazenil if you have recently taken an antidepressant such as amitriptyline
doxepin
clomipramine
desipramine
imipramine
or nortriptyline . Other drugs may affect flumazenil
including prescription and over-the-counter medicines
vitamins
Pregnancy & Lactation
Pregnancy
Caution advised
Lactation
Caution advised
Storage
Inj
Price Intelligence
Rs 33,034.35
DVAGO observed price · per pack of 5 · as of 30 July 2026
Rs 6,606.87 per unit
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 26,389.5
DVAGOper pack of 5Rs 33,034.35
Should you consider an alternative?
Other options containing Flumazenil, and what they are not.
Different molecules used for the same condition. A clinical decision, not a swap.
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Ropicain
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Rs 226.1Rs 226.1/unit
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Rs 442.25Rs 88.45/unit
EFACURIM
50MG/5ML
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Rs 1,239.75Rs 247.95/unit
Xyloaid
2% 10ml
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Rs 1,844Rs 36.88/unit
No DRAP alerts
Propofol
20ml 1% 200mg/20ml
Propofol 10 Mg
Rs 3,030.55Rs 606.11/unit
Precidex
2ml
Dexmedetomidine
Rs 3,325Rs 1,662.5/unit
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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