Drug Identity
Active Ingredient
Gliclazide
Chemical Class
Sulphonyl Urea
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
A10BB09
Status
Essential Medicine
What is Azide?
Uses
Gliclazide is a sulfonyl urea compound. Gliclazide is oral hypoglycemic agent and effective in the treatment of non-insulin dependent dia...
How It Works
Chemical Class
Sulphonyl Urea
Pharmacological Group
on the basis of mechanism of action and also classified in Antidiabetic Agent, Sulfonylurea pharmacological group
It is of Synthetic origin and belongs to Sulphonyl Urea. It belongs to Potassium Channel (ATP sensitive) antagonist pharmacological group on the basis of mechanism of action and also classified in Antidiabetic Agent, Sulfonylurea pharmacological group. The Molecular Weight of Gliclazide is 323.40. Its pKa is 5.8.
How to Take It
1
Adult · PO
40 to 80 mg — 24 hourly
Max dose 320 mg. doses > 160 mg given in 2 divided doses.
2
Child
Not recommended in this age group
Safety Alerts
Gliclazide is contraindicated in conditions like IDDM, Ketosis
Important Warnings
Should not be used in severe renal impairment
Not recommended in pregnancy
Side Effects
The severe or irreversible adverse effects of Gliclazidewhich give rise to further complications include GI symptomsLiver problemsDermatological reactionsHypoglycemia. Gliclazide produces potentially life-threatening effects which include HypoglycemiaBrain damagewhich are responsible for the discontinuation of Gliclazide therapy. The signs and symptoms that are produced after the acute overdosage of Gliclazide include HypoglycemiaCerebral edema. The symptomatic adverse reactions produced by Gliclazide are more or less tolerable and if they become severethey can be treated symptomaticallythese include DizzinessHeadacheNauseaVomitingSkin rashesGI upset
Drug Interactions
Gliclazide is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAspirinClofibrateDiazoxidePhenylbutazone RifampicinSulphamethizoleGliclazide may be displaced from protein binding sites or their metabolism may be inhibited by some sulfonamides
resulting in increased or prolonged effects or toxicity.Dosage adjustments may be necessary during and after sulfonamide therapy These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab Store in a well closed container, Below 40°C. Protect from Sunlight.
Price Intelligence
Rs 186.5
DRAP approved maximum price · per pack of 20 · approved 23 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 20Rs 186.5
Should you consider an alternative?
Other options containing Gliclazide, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Diamicron
80Mg
Rs 284.2Rs 14.21/unit
Lowest price per unitSERVIER PHARMA
Macazid
80mg
Rs 114.76
Macter International Limited
Nidonil
80mg
Rs 121
Below approved ceilingNo DRAP alertsMartin Dow Marker Limited
Glimicroneach
80mg
Rs 172.98
No DRAP alertsUniMark Pharmaceuticals Pvt. Ltd.
Diamicrongliclazide
80mg
Rs 471.05
No DRAP alertsServier Research and Pharmaceuticals (Pakistan) (Pvt) Limited
Nodibet
80mg
Rs 237.8 ceiling
STANDPHARM PAKISTAN (PVT) LTD.
Glimicron
80mg
Rs 172.98 ceiling
No DRAP alertsUniMark Pharmaceuticals Pvt. Ltd.
Diocid
80mg
Rs 250.03 ceiling
No DRAP alertsHIMONT PHARMACEUTICALS (PVT) LTD.
Glinext
80mg
Rs 181.52 ceiling
No DRAP alertsNext Pharmaceutical Products (Pvt.) Ltd
Diozide
80mg
Rs 168.36 ceiling
MEDIPAK LIMITED
Hilzide
80mg
Rs 176.9 ceiling
HILTON PHARMA (PVT) LIMITED
Gliclamed
80mg
Rs 160.13 ceiling
Mediate Pharmaceutical Pvt Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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