Drug Identity
Active Ingredient
Clozapine
Chemical Class
Diazepine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
N05AH02
Status
Essential Medicine
What is Biopine?
schizophrenia
used to treat schizophrenia in adults after other treatments have failed
How It Works
Chemical Class
Diazepine
Pharmacological Group
on the basis of mechanism of action and also classified in Psychotherapeutic Drugs pharmacological group
It is of Synthetic origin and belongs to Diazepine. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs pharmacological group. The Molecular Weight of Clozapine is 326.82.
How to Take It
1
Adult · PO
12.5 mg — As recommended.
Once or twice on day 1.
2
Adult · PO
25 mg — As recommended.
Once or twice on day 2.
3
Adult · PO
25 to 50 mg — 12 hourly
Over 2-3 weeks.
4
Adult
Scraped Dose
Take clozapine exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your
5
Child
Not recommended in this age group
Safety Alerts
Clozapine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use
You should not take clozapine if you are allergic to it
To make sure this medicine is safe for you, tell your doctor if you have ever had: heart problems, high blood pressure , a heart attack or stroke (including "mini-stroke")
long QT syndrome (in you or a family member)
an electrolyte imbalance (such as low levels of potassium or magnesium in your blood)
Important Warnings
Clozapine affects your immune system
You may get infections more easily, even serious or fatal infections
Call your doctor if you have a fever, sore throat , weakness, or lack of energy
Clozapine can increase your risk of seizure, especially at high doses
Avoid any activity that could be dangerous if you have a seizure or lose consciousness
Clozapine can cause serious heart problems
Call your doctor right away if you have chest pain, trouble breathing, fast or pounding heartbeats or sudden dizziness
Clozapine is not approved for use in older adults with dementia -related psychosis
Side Effects
Get emergency medical help if you have signs of an allergic reaction to clozapine ( hivesdifficult breathingswelling in your face or throat) or a severe skin reaction (feversore throatburning eyesskin painred or purple skin rash with blistering and peeling). You may get infections more easilyeven serious or fatal infections. Call your doctor right away if you have signs of infection such as: feverflu-like symptomsextreme weaknessmouth soresskin soresnew or worsening coughtrouble breathingpain or burning when you urinate
Drug Interactions
When you start or stop taking clozapine
your doctor may need to adjust the doses of any other medicines you take on a regular basis. Clozapine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections
asthma
heart problems
high blood pressure
depression
mental illness
cancer
Storage
Tab Store Below 40°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 1,520.69
DRAP approved maximum price · per pack of 50 · approved 04 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 50Rs 1,520.69
Should you consider an alternative?
Other options containing Clozapine, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Glipin
25Mg
Rs 184.3Rs 18.43/unit
Lowest price per unitBelow approved ceilingGLITZ PHARMA
Cloztec
25mg
Rs 1,574.46
PANACEA PHARMACEUTICALS
Zacloz
25mg
Rs 1,642.16
No DRAP alertsM/s. Genix Pharma (Pvt) Ltd.
Lozep
25mg
Rs 1,520.65 ceiling
No DRAP alertsVALOR PHARMACEUTICALS
Bio-Zapine
25mg
Rs 1,616.23 ceiling
BIO LABS (PVT) LTD.
Saveril
25mg
Rs 1,480.08 ceiling
No DRAP alertsDANAS PHARMACEUTICALS (PVT) LTD
Zydex
25mg
Rs 1,595.61 ceiling
No DRAP alertsGENOME PHARMACEUTICALS (PVT) LTD
CLZA
25mg
Rs 1,552.27 ceiling
SEMOS PHARMACEUTICALS (PVT) LTD.
Clozegal
25mg
Rs 1,477.27 ceiling
No DRAP alertsNAVEGAL LABORATORIES
Clozin
25mg
Rs 1,651.92 ceiling
No DRAP alertsNovaMed Pharmaceuticals(Pvt.)Ltd
Sifrenia
25mg
Rs 1,674.91 ceiling
No DRAP alertsM/s Daneen Pharma (Pvt) Ltd
Amlepo
25mg
Rs 1,652.25 ceiling
Amarant Pharmaceuticals Private Limited
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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