Drug Identity
Active Ingredient
Bupivacaine
Drug Class
Anaesthetic, Local
ATC Code
N01BB01
Status
Essential Medicine
What is Bucane?
Uses
Exparel (bupivacaine) is an anesthetic (numbing medicine) that is used after surgery to provide: Local analgesia (pain relief in a small ...
How It Works
Administered by infiltration or by epidural, spinal, or peripheral or sympathetic nerve block as a single injection or repeat injections. Injection should be made slowly. Product containing preservatives should not be used for epidural or caudal block.
How to Take It
1
Adult · Intra Thecal
50 to 100 mg — As recommended.
As Required
2
Child · Intra Thecal
1.25 mg/kg — As recommended.
As Required
Safety Alerts
Application to the middle ear (can cause ototoxicity), avoid injection into infected tissues or inflamed tissues and damaged skin, complete heart block
Children below 12 years not recommended,
Important Warnings
Cardiovascular disease, cerebral atheroma, debilitated patients and elderly (consider dose reduction), epilepsy, hypertension, hypotension, hypovolaemia, impaired cardiac conduction, impaired respiratory function, myasthenia gravis, myocardial depression may be more severe and more resistant to treatment, shock, hepatic impairment
To avoid excessive dosage in obese patients, dose should be calculated on the basis of ideal body-weight
Side Effects
Arrhythmiasblurred visioncardiac arrestconvulsionsdizzinessdrowsinessfeeling of inebriationheadachelightheadednessmuscle twitchingmyocardial depression (resulting in hypotension and bradycardia)nauseanumbness of the tongue and perioral regionparaesthesia (including sensations of hot and cold)peripheral vasodilatation (resulting in hypotension and bradycardia)
Drug Interactions
Other drugs may interact with Exparel
including prescription and over-the-counter medicines
vitamins
and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using including: Lidocaine or other non-bupivacaine local anesthetics: Do not mix. Exparel may be administered at least 20 minutes or more following local administration of lidocaine Bupivacaine HCl: Do not exceed a milligram dose of bupivacaine HCl solution to Exparel of 1:2 when admixing
as this may impact the pharmacokinetics and/or physicochemical properties of the drugs.
Storage
Inj Store at room temperature. Do not Freeze. Protect from Sunlight.
Price Intelligence
Rs 350.17
DRAP approved maximum price · per pack of 5 · approved 27 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
No retail prices recorded
Should you consider an alternative?
Other options containing Bupivacaine, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Nervlok
5mg
Rs 210.78 ceiling
SURGE LABORATORIES (PVT) LTD.
Nervlok-Heavy
5mg
Rs 329.15 ceiling
SURGE LABORATORIES (PVT) LTD.
Hospicaine
5mg
Rs 210.78 ceiling
The Searle Company Limited
Neupivac
5mg
Rs 142.56 ceiling
NEUTRO PHARMA (PVT) LTD.
Pivacain
5mg
Rs 184.44 ceiling
Bajwa Pharmaceuticals (Pvt.) Ltd.
Pivacan
5mg
Rs 200.85 ceiling
No DRAP alertsWimits Pharmaceuticals Pvt. Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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