Drug Identity
Active Ingredient
Calcium
Chemical Class
water soluble vitamin
ATC Code
A12A, A12AA, A12AA03, D11AX03
Status
Essential Medicine
What is Calfoli?
Uses
Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. L...
How It Works
Chemical Class
water soluble vitamin
It is of Synthetic origin and belongs to water soluble vitamin. It belongs to Hematological Agents and Antidotes pharmacological group. The Molecular Weight of Folinic Acid is 473.40. Its pKa is 3.1, 4.8, 10.4.
How to Take It
1
Adult · IV,IM
120 mg — As recommended.
In div.doses over 12-24 hrs.
Safety Alerts
You should not receive this medicine if you are allergic to levoleucovorin, folic acid, or folinic acid
If possible, before you receive levoleucovorin, tell your doctor or caregivers if you have: kidney disease
or if you are dehydrated
It is not known whether levoleucovorin will harm an unborn baby
Tell your doctor if you are pregnant or plan to become pregnant
Important Warnings
You should not be treated with this medication if you are allergic to levoleucovorin or to folic acid or folinic acid
Tell your doctor if you are taking sulfa drugs, seizure medication, a cancer medication called fluorouracil (5FU), or a multivitamin or mineral supplement than contains folic acid
In an emergency situation, it may not be possible before you are treated to tell your caregivers about all of your medical conditions or if you are pregnant or breast-feeding
However, make sure any doctor caring for you afterward knows that you have received levoleucovorin
Tell your doctor or caregivers at once if you have fever, chills, white patches or sores inside your mouth or on your lips, severe or ongoing diarrhea, confusion, urination problems, or if you feel very thirsty or hot, if you are unable to urinate, and you have heavy sweating or hot and dry skin
Side Effects
Get emergency medical help if you have any signs of an allergic reaction to levoleucovorin: hivesdifficult breathingswelling of your facelipstongueor throat. Tell your doctor or caregivers at once if you have: blisters or ulcers in your mouthred or swollen gumstrouble swallowingsevere or ongoing diarrheaa light-headed feelinglike you might pass outseizure (convulsions)dehydration symptoms - feeling very thirsty or hotbeing unable to urinateheavy sweating
Drug Interactions
Tell your doctor about all medicines you use
and those you start or stop using during your treatment with levoleucovorin
especially: seizure medicine - phenobarbital
phenytoin
primidone
a multivitamin or mineral supplement than contains folic acid
or a sulfa drug (Bactrim
Septra
Storage
Tab, Inj Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 912.37
DRAP approved maximum price · per unit · approved 01 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
No retail prices recorded
Should you consider an alternative?
Other options containing Calcium, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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