Cestonilplus

CESTONIL PLUS

Pizotifen

Raazee Therapeutics (Pvt Ltd.

Drug Identity

Active Ingredient
Pizotifen
Drug Class
Neuro
Chemical Class
Thiopyrimidine
0

What is Cestonilplus?

Uses
Fedratinib is used to treat intermediate-2 or high-risk primary or secondary myelofibrosis (MF) in adults, relieving night sweats, itchin...

How It Works

Chemical Class
Thiopyrimidine

Thiamine HCl (Vitamin B1) also known as Thiamin/Fursultiamine. It is of Synthetic origin and belongs to Thiopyrimidine. It belongs to Vitamin, Water Soluble pharmacological group. The Molecular Weight of Thiamine HCl (Vitamin B1) is 337.30. It is strongly acidic drug, 4.24% solution of the drug is isotonic and Its pKa is 4.8.

How to Take It

1
Adult · PO,IM
100 to 300 mg — 24 hourly
IV doses should be administered slowly atleast over 20 min to reduce Idiosyncratic reactions
2
Adult
Scraped Dose
Take fedratinib exactly as prescribed by your doctor. Follow all directions on your Inrebic (fedratinib) Package Insert and read all medication guides or instruction sheets. Your doctor may occasio
3
Child · Intra Muscular
1 mg/kg — 24 hourly
-
4
Child · Oral
1 mg/kg — 24 hourly
-

Safety Alerts

To make sure fedratinib is safe for you, tell your doctor if you: have low vitamin B1 (thiamine) levels have low red blood cell or platelet counts have or have had liver problems have or have had kidney problems have or have had eye problems are a current or past smoker have had a blood clot, heart attack, other heart problems, or stroke have or have had any other cancer are pregnant or plan to become pregnant are breastfeeding or plan to breastfeed
Fedratinib is not for use in patients under the age of 18 years

Important Warnings

Patients with narrow angle glaucoma or urinary retention (dueto slight anticholinergic effect of pizotifen), pregnancy and lactation

Side Effects

Sedationdizzinessdry mouthconstipation.

Drug Interactions

Sedatives
hypnotics
antihistamines
alcohol.

Storage

Inj Store Below 40°C. Do not Freeze. Protect from Sunlight. Tab Store in a well closed container, Below 40°C. Protect from Sunlight.

Price Intelligence

Rs 125
Servaid observed price · as of 30 July 2026
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 125

Should you consider an alternative?

Other options containing Pizotifen, and what they are not.

These contain this ingredient plus others. They are different medicines — do not swap.

Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.

For pharma professionalsCompany, market and opportunity intelligence

Company

Prices as of 30 July 2026 · DRAP ceiling as of 30 July 2026 · schema v3-SKU

For medicine intelligence and professional reference only. Not medical advice.