Drug Identity
Active Ingredient
Chlorophinicol Sodium
Drug Class
Amphenicols
ATC Code
D06AX02, D10AF03, G01AA05, J01BA01, S01AA01, S02AA01, S03AA08
Status
Essential Medicine
What is CHLORAMPHENICOL?
Uses
It is used to treat bacterial infections.
How It Works
IV: Infuse via direct IV over 3-5 min; intermittent infusion over 30-60 min. IM: Do not administer IM.
How to Take It
1
Adult · Ophthalmic
0.5 %w/v — 2 hourly
2
Adult · Ophthalmic
1 %w/w — 6 hourly
Frequency may be increased to 8 times if needed.
3
Adult · Otic
5 to 10 % — 6 hourly
1-2 drops.
4
Adult · PO,IV
50 to 100 mg/kg — 6 hourly
Maximum dose: 4 g/day.
5
Child · Intra Venous
12.5 to 25 mg/kg — 6 hourly
-
6
Child · Oral
12.5 to 25 mg/kg — 6 hourly
-
Safety Alerts
Acute porphyria, history of previous hypersensitivity or toxicity with chloramphenicol, severe renal impairment
Important Warnings
Avoid repeated courses and prolonged treatment, reduce dose in hepatic and renal impairment, blood counts required before and periodically during treatment, monitor plasma-chloramphenicol concentrations in neonates, risk of serious and fatal blood dyscrasias
Chloramphenicol must not be used when less potentially dangerous agents are effective Associated with serious haematological side-effects when given systemically and should therefore be reserved for the treatment of life-threatening infections
Side Effects
Blood disordersdepressiondiarrhoeadry moutherythema multiformeglossitisheadachenauseanocturnal haemoglobinuriaoptic neuritisperipheral neuritisreversible and irreversible aplastic anaemia (with reports of resulting leukaemia)stomatitisurticariavomiting
Drug Interactions
Rifampicin
warfarin
sulphonylureas
phenobarbital
phenytoin
cyclosporin
tacrolimus.
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Contraindicated, avoid
Storage
Caps, Oral Susp, Dry Powder for Inj Store at room temperature. Protect from Sunlight. Cream, Syrup, Eye Ointment, Eye Drops, Ear Soln Store in a well closed container, at room temperature. Do not Freeze. Protect from Sunlight. Inj (reconstituted soln) Store at room temperature. Use within 24-48 hrs if kept at room temperature.
Price Intelligence
Rs 63.09
DRAP approved maximum price · per pack of 12 · approved 22 Aug, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 12Rs 63.09
Should you consider an alternative?
Other options containing Chlorophinicol Sodium, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Mediphenicol
5ml
Rs 24.91
Mediate Pharmaceutical Pvt Ltd
Neophenicol
5ml
Rs 62.74
No DRAP alertsP.D.H. PHARMACEUTICALS (PVT) LTD.
Neophenicol
125mg
Rs 62.74 ceiling
No DRAP alertsP.D.H. PHARMACEUTICALS (PVT) LTD.
Mediphenicol
125mg
Rs 24.91 ceiling
Mediate Pharmaceutical Pvt Ltd
Optachloreye
10ml
+ Eye
Rs 17.87
No DRAP alertsRemington Pharmaceuticals Industries
Optachlor Eye
5g
+ Eye
Rs 34.7Rs 34.7/unit
No DRAP alertsREMINGTON PHARMACEUTICAL IND
Optachlor Eye
0.5% 10Ml
+ Eye
Rs 46.55Rs 46.55/unit
No DRAP alertsREMINGTON PHARMACEUTICAL IND
Chloropticeye
10ml
+ Eye
Rs 65.97
No DRAP alertsBarrett Hodgson Pakistan (Private) Ltd.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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