Drug Identity
Active Ingredient
Clomipramine
Drug Class
Neuro
Chemical Class
Imipramine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
N06AA04
Status
Essential Medicine
What is Clomfranil?
Uses
Clomipramine (HCl) is a tricyclic antidepressant. Clomipramine (HCl) is used in the treatment of (OCD) obsessive compulsive disorders (me...
How It Works
Chemical Class
Imipramine
Pharmacological Group
on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant pharmacological group
It is of Synthetic origin and belongs to Imipramine. It belongs to Amine uptake inhibitor pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant pharmacological group. The Molecular Weight of Clomipramine (HCl) is 314.90. It is weakly alkaline drug and Its pKa is 9.5.
How to Take It
1
Adult · PO
25 mg — 24 hourly
Initial, gradually increased
2
Child
200 mg/day — 24 hourly
3
Child · PO
0 to 3 mg — As recommended.
initial, gradually incteased.To a maximum of 100mg/kg daily.
Safety Alerts
Arrhythmias, acute porphyrias, during manic phase of bipolar disorder, heart block, immediate recovery period after myocardial infarction, severe liver disorder
Important Warnings
Cardiovascular disease (risk of sudden death), hepatic impairment (avoid if severe), diabetes, epilepsy, history of bipolar disorder, history of psychosis or mania, chronic constipation, hyperthyroidism, increased intra-ocular pressure, patients with risk of suicide, phaeochromocytoma, prostatic hypertrophy, susceptibility to angle-closure glaucoma, urinary retention, withdraw gradually
Side Effects
Agitationanorexiafatiguehypertensionmydriasisoedemapalpitationrestlessnessstomatitisblurred visionconfusionconstipationconvulsionsdelusionsdizziness
Drug Interactions
With or within 3 weeks of MAOls
other antidepressants
CNS depressants
antipsychotics
anticoagulants
anticholinergics
antihypertensives
sympathomimetics
Pregnancy & Lactation
Pregnancy
Avoid unless potential benefit outweighs risk
Lactation
Contraindicated, avoid
Storage
Caps Store in a well closed container, Below 40°C. Protect from Sunlight.
Price Intelligence
Rs 72.2
DVAGO observed price · per pack of 10 · as of 30 July 2026
Rs 7.22 per unit
Prices across sources
ServaidRs 502
DVAGOper pack of 10Rs 72.2
DRAPper pack of 100Rs 797.07
Should you consider an alternative?
Other options containing Clomipramine, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Clomipera
25mg
Rs 276.12
No DRAP alertsMEDERA PHARMACEUTICALS (PVT) LTD.
Clopra
25mg
Rs 276.12 ceiling
No DRAP alertsMEDERA PHARMACEUTICALS (PVT) LTD.
Anafril
25mg
Rs 141.65 ceiling
Glitz Pharma
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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