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Drug Identity
Active Ingredient
Hydrochlorothiazide
Drug Class
Angiotensin-Ii Antagonists, Combinations
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C03AA03
Status
Essential Medicine
What is Co-Olesta?
Uses
Hydrochlorothiazide is a prototype drug of thiazide diuretics. Hydrochlorothiazide is antihypertensive agent. It increases the urination ...
How It Works
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group
It is of Synthetic origin and belongs to Thiazide. It belongs to NaCl cotransport inhibitor pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group. The Molecular Weight of Hydrochlorothiazide is 297.74. Its pKa is 7.9, 9.2.
How to Take It
1
Adult · PO
25 to 100 mg — 24 hourly
As Required
2
Child · Oral
2.5 mg/kg — 12 hourly
Safety Alerts
Hepatic or severe renal impairment, cholestasis, biliary obstructive disorders, refractory hypoka-laemia, hypercalcaemia, hyponatraemia, symptomatic hyperuricaemia
Important Warnings
Salt or volume depletion, severe congestive heart failure, renal disease, renal artery stenosis, aortic or mitral valve stenosis, obstructive hypertrophic cardiomyopathy, primary aldosteronism, diabetes, mild to moderate renal impairment
monitor serum electrolytes, creatinine and uric acid
Side Effects
Arthritischest paincoughfatigueGI disturbanceshaematuriahypertriglyceridaemiahyperuricaemiainfluenza-like symptomsmusculoskeletal painperipheral oedemapharyngitisrhinitisurinary-tract infection. Rare: Anginavertigo
Drug Interactions
Lithium
K-supplement
K+-sparing diuretics
salt substitutes
baclofen
NSAIDs
amifostine
alcohol
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Storage
Store in a well closed container, at room temperature. Protect from Moisture and Heat. Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 234.7
DVAGO observed price · per pack of 10 · as of 30 July 2026
Rs 23.47 per unit
No approved ceiling matched to this exact pack and strength.
Prices across sources
DVAGOper pack of 10Rs 234.7
ServaidRs 210
Should you consider an alternative?
Other options containing Hydrochlorothiazide, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Co-Baritec
12.5mg
Rs 237.5Rs 23.75/unit
Lowest price per unitNo DRAP alertsBARRETT HODGSON PAKISTAN
Co-Baritec
12.5Mg
Rs 456Rs 45.6/unit
No DRAP alertsBARRETT HODGSON PAKISTAN
Omsanadiu
12.5mg
Rs 364.98
HILTON
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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