Drug Identity
Active Ingredient
Trimethoprim
Chemical Class
Pyrimidine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
J01EA01
Status
Essential Medicine
What is Cotrifa?
Uses
Trimethoprim is an antibiotic that is used to treat bladder or kidney infections , or ear infections caused by certain bacteria. Trimetho...
How It Works
Chemical Class
Pyrimidine
Pharmacological Group
on the basis of mechanism of action and also classified in Antibiotics pharmacological group
It is of Synthetic origin and belongs to Pyrimidine. It belongs to Dihydrofolate reductase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotics pharmacological group. The Molecular Weight of Trimethoprim is 290.30. Its pKa is 7.3.
How to Take It
1
Adult · PO
300 mg — 24 hourly
For 7-Days
2
Adult
Scraped Dose
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Measure liquid medicine carefully. Use the dosing syring
3
Child · Oral
4 mg/kg — 12 hourly
-
Safety Alerts
You should not use trimethoprim if you are allergic to it, or if you have: anemia (low red blood cells) caused by a folate (folic acid) deficiency
Trimethoprim is not approved for use by anyone younger than 2 months old
Trimethoprim should not be used to treat an ear infection in a child younger than 6 months old
Tell your doctor if you have ever had: a folate deficiency
liver or kidney disease
Important Warnings
You should not use trimethoprim if you have anemia caused by a folate ( folic acid ) deficiency
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hivesdifficult breathingswelling of your facelipstongueor throat. Trimethoprim may cause serious side effects. Call your doctor at once if you have: severe stomach paindiarrhea that is watery or bloody (even if it occurs months after your last dose)palegrayor bluish skinfeverweaknesssore or swollen tongueeasy bruisingpurple or red spots under your skin
Drug Interactions
Other drugs may affect trimethoprim
including prescription and over-the-counter medicines
vitamins
and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.
Storage
Tab Store Below 40°C.
Price Intelligence
Rs 20.96
DRAP approved maximum price · per 50ml · approved 20 Aug, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper 50mlRs 20.96
Should you consider an alternative?
Other options containing Trimethoprim, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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