Cytosar

Can be administered IM, IV Infusion, IT or SC at a concentration NTE 100 mg/ ml IV may be administered either as a bolus, IVPB (high doses of >500 mg/m2), or continuous IV infusion (doses of 100-200 mg/m2). Reconstitute with SWFI, D5W or NS. Standard IV infusion dilution: Dose 250/1000 ml D5W or NS. Standard intrathecal dilution: Dose 3-5 ml lactated Ringers + methotrexate (12 mg) + hydrocortisone (15-50 mg). Note: Bacteriostatic diluent should not be used for the preparation of either high doses or intrathecal doses of cytara-bine; may be used for IM, SC, and low-dose (100-200 mg/ m2) IV Solution.