Drug Identity
Active Ingredient
Cholecalciferol
Chemical Class
Sterol
What is Definity?
Uses
Cholecalciferol is a naturally occurring form of vitamin D (a fat-soluble vitamin). Cholecalciferol is produced from 7-dehydrocholesterol...
How It Works
Chemical Class
Sterol
Cholecalciferol also known as Cholecalciferol. It is of Natural origin and belongs to Sterol. The Molecular Weight of Cholecalciferol is 384.64.
How to Take It
1
Adult · PO
400 to 1000 units — 24 hourly
2
Adult
Scraped Dose
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product Capsule, Oral: D3-50: 1250 mcg (50000 unit) [dai
Safety Alerts
Cholecalciferol is contraindicated in conditions like Hypercalcemia, Hypersensitivity to any component of product
Important Warnings
Concerns related to adverse effects: • Vitamin D toxicity: May occur with excessive doses
symptoms may include nausea, vomiting, loss of appetite, constipation, dehydration, fatigue, irritability, confusion, weakness and/or weight loss
Effects of vitamin D can last ≥2 months after therapy is discontinued
Disease related concerns: • Hyperphosphatemia: Normal serum phosphorous concentrations must be maintained in patients treated for hyperphosphatemia to prevent metastatic calcification
• Obesity: Adults with a BMI >30 kg/m 2 are at high risk for vitamin D deficiency due to storage of vitamin D in adipose tissue
Doses higher than the RDA may be required, but must be carefully monitored to avoid toxicity
• Renal impairment: Metabolism of vitamin D may be altered in patients with chronic kidney disease
Supplementation with cholecalciferol may be needed
Side Effects
The severe or irreversible adverse effects of Cholecalciferolwhich give rise to further complications include HypercalciuriaRenal damageHypercalcemia. The signs and symptoms that are produced after the acute overdosage of Cholecalciferol include NauseaVomitingDiarrheaPolyuriaSweatingHeadacheAnorexiaVertigoThirstlassitude. The symptomatic adverse reactions produced by Cholecalciferol are more or less tolerable and if they become severethey can be treated symptomaticallythese include Anorexia
Drug Interactions
Aluminum Hydroxide: Vitamin D Analogs may increase the serum concentration of Aluminum Hydroxide. Specifically
the absorption of aluminum may be increased
leading to increased serum aluminum concentrations. Avoid combination Bile Acid Sequestrants: May decrease the serum concentration of Vitamin D Analogs. More specifically
bile acid sequestrants may impair absorption of Vitamin D Analogs. Management: Avoid concomitant administration of vitamin D analogs and bile acid sequestrants (eg
cholestyramine). Separate administration of these agents by several hours to minimize the potential risk of interaction. Monitor plasma calcium concentrations. Consider therapy modification Calcium Salts: May enhance the adverse/toxic effect of Vitamin D Analogs. Monitor therapy Cardiac Glycosides: Vitamin D Analogs may enhance the arrhythmogenic effect of Cardiac Glycosides. Monitor therapy Danazol: May enhance the hypercalcemic effect of Vitamin D Analogs. Monitor therapy Erdafitinib: Serum Phosphate Level-Altering Agents may diminish the therapeutic effect of Erdafitinib. Management: Avoid coadministration of serum phosphate level-altering agents with erdafitinib before initial dose increase period based on serum phosphate levels (Days 14 to 21). Consider therapy modification Mineral Oil: May decrease the serum concentration of Vitamin D Analogs. More specifically
mineral oil may interfere with the absorption of Vitamin D Analogs. Management: Avoid concomitant
oral administration of mineral oil and vitamin D analogs. Consider separating the administration of these agents by several hours to minimize the risk of interaction. Monitor plasma calcium concentrations. Consider therapy modification Multivitamins/Fluoride (with ADE): May enhance the adverse/toxic effect of Vitamin D Analogs. Avoid combination Multivitamins/Minerals (with ADEK
Folate
Storage
Tabs,caps Store in a well closed container, at room temperature, Between 15°C-30°C. Protect from Sunlight, Moisture and Heat.
Price Intelligence
Rs 862.33
DRAP approved maximum price · 5'sx 1ml · approved 27 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAP5'sx 1mlRs 862.33
Should you consider an alternative?
Other options containing Cholecalciferol, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Cholced
5mg/ml
Rs 213.57
No DRAP alertsMaxitech Pharma (Pvt) Ltd. DML: 000851
Calbondd
5mg/ml
Rs 903.7
No DRAP alertsPDH LABORATORIES (PVT) LTD
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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