Drug Identity
Active Ingredient
Isosorbide
Drug Class
Cardiac Therapy
What is Di-Card?
Uses
Isosorbide dinitrate is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the...
How It Works
By IV infusion diluted to a max concentration of 0.05% in NS or D5W. Also administered as an intra-coronary bolus inj during percutaneous transluminal coronary angioplasty
How to Take It
1
Adult
Scraped Dose
Before using isosorbide dinitrate to treat a sudden angina attack, your doctor may want you to first use a nitroglycerin sublingual tablet. Follow your doctor's instructions about what medications
Safety Alerts
Hypersensitivity to nitrates
hypotensive conditions and hypovolaemia
hypertrophic cardiomyopathy
cardiac tamponade
constrictive pericarditis
Important Warnings
Hypothyroidism, malnutrition, hypothermia, recent history of myocardial infarction, heart failure due to obstruction, hypoxaemia or other ventilation and perfusion abnormalities, susceptibility to angle-closure glaucoma, metal-containing transdermal systems should be removed before magnetic resonance imaging procedures, cardioversion, or diathermy, avoid abrupt withdrawal, monitor blood pressure and heart rate during IV infusion
Side Effects
Postural hypotensiontachycardiaparadoxical bradycardiathrobbing headachedizzinessnauseavomitingheartburnflushingsyncopetemporary hypoxaemiarash. Rare: angle-closure glaucoma. Injection Specific side-effects include severe hypotensiondiaphoresisapprehensionrestlessness
Drug Interactions
Sildenafil
tadalafil
vardenafil
ethanol
heparin
alteplase
ergot alkaloids.
Pregnancy & Lactation
Pregnancy
Caution advised, avoid unless potential benefit outweighs risk.
Lactation
Caution advised
Storage
Tab Store in a well closed container, Below 40°C. Protect from Moisture and Heat.
Price Intelligence
Rs 58.26
DRAP approved maximum price · per pack of 100 · approved 22 Aug, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 100Rs 58.26
Should you consider an alternative?
Other options containing Isosorbide, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Isdin
10mg
Rs 19Rs 1.9/unit
Lowest price per unitBelow approved ceilingMAPLE PHARMA
Mantan
10mg
Rs 75.83 ceiling
No DRAP alertsZephyr Pharmatec (pvt) limited
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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