Drug Identity
Active Ingredient
Thioridazine
Drug Class
Other Analgesics And Antipyretics
Chemical Class
Phenothiazine
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Diagesicp?
Uses
Thioridazine (HCl) is a phenothiazine, similar to chlorpromazine. Thioridazine (HCl) is used in the treatment of certain mental disorders...
How It Works
Chemical Class
Phenothiazine
Pharmacological Group
on the basis of mechanism of action and also classified in Psychotherapeutic Drugs pharmacological group
It is of Synthetic origin and belongs to Phenothiazine. It belongs to D2 antagonist pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs pharmacological group. The Molecular Weight of Thioridazine (HCl) is 407.00. Its pKa is 9.5.
How to Take It
1
Adult · PO
50 to 300 mg — 24 hourly
For psychotic out patients.
2
Adult · PO
100 to 600 mg — 24 hourly
For hospitalized psychotic patients.
3
Child · Oral
0.5 to 2 mg/kg — 12 hourly
-
Safety Alerts
Contains phenothiazine, avoid regular use as analgesic
Important Warnings
Thioridazine should be used with caution in patients exposed to extreme heat or phosphorus insecticides, patients in state of alcohol withdrawal, patients with history of peptic ulcer, allergic reactions, with renal (kidney) impairment, prostatic hypertrophy
Photosensitization may occur, caution patients against exposure to sunlight or UV light
Discontinue use at least 48 hrs before myelography
Side Effects
The severe or irreversible adverse effects of Thioridazine (HCl)which give rise to further complications include Tardive dyskinesiaAcute dyskinesiaPigmentary retinopathy. Thioridazine (HCl) produces potentially life-threatening effects which include AgranulocytosisArrhythmiasNeuroleptic Malignant SyndromeCardiac Arrest. which are responsible for the discontinuation of Thioridazine (HCl) therapy. The signs and symptoms that are produced after the acute overdosage of Thioridazine (HCl) include HypotensionCardiac arrhythmiasComaEpileptic seizuresLoss of reflexesShallow breathingMotor restlessnessHyperflexia. The symptomatic adverse reactions produced by Thioridazine (HCl) are more or less tolerable and if they become severethey can be treated symptomatically
Drug Interactions
Thioridazine (HCl) is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdrenalineAlcoholAmitriptyline (HCl)coadministration of these two drugs can cause increase in plasma concentration of both drugs that result in central nervous system depression
hypotension and prolong QT interval.ModerateCombine use of these drugs should be avoided.AtenololBoth agents act additively and produce hypotensive and central nervous system depressant effect.ModerateClosely monitor for hypotension and prolonged CNS depression. Patient should notify to physician about excessive side effects.Dapoxetine HCl Dapoxetine inhibits the metabolism of thioridazine and the resulting elevated levels of thioridazine are expected to augment the prolongation of the QTc interval.Dapoxetine should not be used in combination with thioridazine DextromethorphanDisopyramideprolongs QT interval results in ventricular arrhythmias
ventricular tachycardia and torsade de pointes. prolongs QT interval results in ventricular arrhythmias
ventricular tachycardia and torsade de pointes. prolongs QT interval results in ventricular arrhythmias
ventricular tachycardia and torsade de pointes. Thioridazine prolongs QT interval results in ventricular arrhythmias
ventricular tachycardia and torsade de pointes. MajorCoadministration is considered contraindicatedDroperidolFosphenytoinGuanethidineLevodopaLithiumCoadministration may initiate the number of neurologic and psychiatric symptoms such as extrapyramidal effects
seizures
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Contraindicated or not recommended. Consult product literature for precautions and side-effects
Storage
Tab Store in a well closed container, Below 40°C. Protect from Sunlight.
Price Intelligence
Rs 204.9
DVAGO observed price · as of 30 July 2026
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 1,500
DVAGORs 204.9
Should you consider an alternative?
Other options containing Thioridazine, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Aksopol
120mg/5ml
Rs 28.58
No DRAP alertsAKSON PHARMACEUTICALS (PVT) LTD.
Febrol
500Mg
Rs 33.6Rs 3.36/unit
Below approved ceilingNo DRAP alertsBARRETT HODGSON PAKISTAN
Patrik
100mg/ml
Rs 34.08
No DRAP alertsWINLET
Panadol
500Mg
Rs 34.5Rs 3.45/unit
Below approved ceilingNo DRAP alertsHALEON
Calpol
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Rs 34.6Rs 3.46/unit
Below approved ceilingGlaxoSmithKline PAKISTAN
Febrol
120mg
Rs 41.44
No DRAP alertsBARRETT HODGSON
Febrol
250mg
Rs 47.39
No DRAP alertsBARRETT HODGSON
Calpol Plus
500Mg 65Mg
Rs 52.5Rs 5.25/unit
GlaxoSmithKline PAKISTAN
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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