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Drug Identity
Active Ingredient
Orphenadrine
Drug Class
Pain Management
Chemical Class
Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents and Muscle Relaxants pharmacological group
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Duragesic?
Uses
Orphenadrine is a muscle relaxer. Orphenadrine is used together with rest and physical therapy to treat skeletal muscle conditions such a...
How It Works
Chemical Class
Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents and Muscle Relaxants pharmacological group
Pharmacological Group
on the basis of mechanism of action and also classified in Antiparkinson Agents and Muscle Relaxants pharmacological group
It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents and Muscle Relaxants pharmacological group. The Molecular Weight of Orphenadrine is 269.40. Its pKa is 9.
How to Take It
1
Adult · PO
100 mg — 12 hourly
2
Adult
Scraped Dose
Follow all directions on your prescription label. Do not take orphenadrine in larger or smaller amounts or for longer than recommended. Orphenadrine may be habit-forming. Never share orphenadrine w
3
Child · Oral
5 to 13.33 mg/kg — 8 hourly
Safety Alerts
Glaucoma, urinary retention, myasthenia gravis
Important Warnings
Tachycardia, impaired renal and hepatic function
Drowsiness may affect performance of skilled tasks (e
effects of alcohol enhanced
Side Effects
Anxietyblurred visionbradycardiacholestatic jaundiceconfusiondizzinessdrowsinessdyspepsiafeverheadachehypersensitivity reactionshypotensionleucopenianasal congestionnausea
Drug Interactions
Taking orphenadrine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill
narcotic pain medicine
prescription cough medicine
a muscle relaxer
or medicine for anxiety
depression
or seizures . Other drugs may interact with orphenadrine
including prescription and over-the-counter medicines
Pregnancy & Lactation
Pregnancy
Avoid unless potential benefit outweighs risk.
Lactation
Caution advised or effect undetermined.
Storage
Tab, Inj Store in a well closed container, Below 40°C. Protect from Sunlight, Moisture and Heat.
Price Intelligence
Rs 55
DVAGO observed price · as of 30 July 2026
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 138.9
DVAGORs 55
Should you consider an alternative?
Other options containing Orphenadrine, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Samerol-N
Rs 35.68Rs 4.46/unit
SAMI PHARM (PVT) LTD.
Wilgesic
450mg 35mg
Rs 66.5Rs 6.65/unit
WILSONS PHARMACEUTICALS
Sinaxamol
450Mg 35Mg
Rs 77.6Rs 7.76/unit
No DRAP alertsAGP PHARMA
Medigesic
35Mg 450Mg
Rs 95Rs 9.5/unit
WILSHIRE LABORATORIES
Nuberol Forte
650Mg 50Mg
Rs 61.75Rs 12.35/unit
SEARLE PAKISTAN (PVT) LTD.
Nuberolforte
650mg
Rs 65.01
SEARLE PAKISTAN (PVT.) LTD.
Para
120mg/5ml
Rs 66.01
REKO
Wilgesic
450mg
Rs 70
WILSONS PHARMACEUTICALS
Sinaxamol
450mg
Rs 81.7
No DRAP alertsAGP
Para
250mg/5ml
Rs 94.97
REKO
Medigesic
35mg
Rs 100
WILSHIRE LABORATORIES (PVT) LTD.
Provasnforte
Rs 105
Sami Pharm (Pvt) Ltd.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
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brands
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5
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