Drug Identity
Active Ingredient
Ephedrine
Chemical Class
Ephedra Alkaloid
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C01CA26, R01AA03, R01AB05, R03CA02, S01FB02
Status
Essential Medicine
What is Elidrine,?
Uses
Ephedrine is used for temporary relief of shortness of breath, chest tightness, and wheezing due to bronchial asthma. Ephedrine may also ...
How It Works
Chemical Class
Ephedra Alkaloid
Pharmacological Group
on the basis of mechanism of action and also classified in Drugs used in Shock and Alpha-Beta Blocker pharmacological group
Eedrynum hidratum, Eedrynum hidratum are the derivatives of Ephedrine It is of Natural/Synthetic origin and belongs to Ephedra Alkaloid. It belongs to Alpha & Beta adrenergic agonist pharmacological group on the basis of mechanism of action and also classified in Drugs used in Shock and Alpha-Beta Blocker pharmacological group. The Molecular Weight of Ephedrine is 165.20. It is weakly acidic drug, 3.20% solution of the drug is isotonic and Its pKa is 9.6.
How to Take It
1
Adult · IM,SC,Slow IV
25 to 50 mg — As recommended.
2
Adult · Nasal drops
0.5 to 1 % — As recommended.
for the treatment of nasal congestion.
3
Adult · PO
25 to 50 mg — 4 hourly
4
Child · Nasal
0.5 to 1 % — As recommended.
As Required
5
Child · Oral
1.5 mg/kg — 8 hourly
-
Safety Alerts
Ephedrine is contraindicated in conditions like Hypertension, Thyrotoxicosis, Ischemic heart disease, Prostatic hypertrophy
Important Warnings
Ephedrine should be used with caution in patients of heart disease, cardiac arrhythmias, angina pectoris, renal impairment, diabetes, hypertension
Carefully monitor BP, Co-administration of a vasopressor and an oxytocic cause serious postpartum hypertension, some patients experienced a stroke
Avoid intraneural and intravascular injection
Side Effects
All medicines may cause side effectsbut many people have noor minorside effects. Check with your doctor if any of these most common side effects persist longer than one hours or become worse: Dizzinessheadachenauseanervousnesstremorloss of appetiterestlessnesssleeplessnessstomach irritation. Seek medical attention right away if any of these severe side effects occur: Severe allergic reactions (rashhivesdifficulty breathingtightness in the chest
Drug Interactions
Ephedrine is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAcetazolamide (Na)AdrenalineAlbuterolShould not use concurrently without doctors prescription.AlcoholDexamethasoneEphedrine increase urinary excretion of DexamethasoneDexamethasoneDoxapramBoth drugs acts additively.Ephedrine exacerbate the adrenergic response to doxapram thus increases the blood pressure and heart rate.ModerateClosely monitor pulse and blood pressureDoxepin (HCl)Ergometrine (Maleate)Both agents acts additively and synergistically to produce vasoconstriction results in increased blood pressure.ModerateConcomitant use is considered contraindicated. Closely monitor for response and tolerance of patient. Ergotamine (Tartrate)Ergotamine significantly increases the blood pressure by synergistic vasoconstriction due to alpha adrenergic agonist activity of ephedrine.ModerateClinical monitoring of response
tolerence and excessive vasoconstriction is recommended. Patient advised to notify if numbness
tingling
muscle pain
weakness and chest pain signs appears.FurazolidoneBoth agents act synergistically affecting the sympathomimetic activity in this way that furazolidone enhances the storage of norepinephrine in adrenergic neuron and ephedrine increases its liberation result in severe hypertension and hyperpyrexia.MajorBoth agents should not be used in combination.There should be gap of atleast 14 days before initiation of ephedrine therapy and discontinuation of therapy with furazolidone.Halothaneconcomitant administration should be avoided with anesthetic such as halothane
cyclopropaneHyoscine (Butylbromide)IsocarboxazidLevodopaMaprotiline (HCl)Maprotiline interfere with the pressor effect of ephedrine.MinorMonitor the patient`s blood pressure regularly.MoclobemideNitroglycerinEphedrine oppose the vasodilatory actions of nitroglycerin and may cause angina. Noradrenaline (Acid Tartrate)OxprenololConcomitant use may cause hypertensive reactions.Oxytocinconcomitant administration may lead to vasoconstrictive effectPhenobarbitonePhenylpropanolamine (HCl)There is an increase in blood pressure and heart rate if this combination is used.ModerateThis combination is used cautiously and should monitor pulse and blood pressure.ProcarbazineBoth agents act synergistically affecting the sympathomimetic activity in this way that procarbazine enhances the storage of norepinephrine in adrenergic neuron and ephedrine increases its liberation result in severe hypertension and hyperpyrexia.MajorBoth agents should not be used in combination.if necessary 14 days discontinuation of procarbazine must take before initiastion of ephedrine therapy.Quinagolide (HCl)Quinidinetheir is risk of arrythmias when ephedrine co administered with cardiac glycosides such as quinidine or TCAsRauwolfia ReserpineReserpineSelegiline (HCl)SibutramineSodium AcetateAlkalization of the urine decreases the urinary excretion increases the elimination half-life of ephedrine.ModeratePatients should be monitored for toxic effects such as tremor
anxiety
Storage
Elixir, Nasal Spray Store in a well closed container, Below 40°C. Do not Freeze. Protect from Sunlight. Tab, Inj, Caps Store in a well closed container, Below 40°C. Protect from Sunlight.
Price Intelligence
Rs 499.82
DRAP approved maximum price · per pack of 5 · approved 12 Dec, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
No retail prices recorded
Should you consider an alternative?
Other options containing Ephedrine, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Vepressor
50mg
Rs 271.6
No DRAP alertsVENUS
Sedaphrine
50mg
Rs 673.69 ceiling
Bajwa Pharmaceuticals (Pvt.) Ltd.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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