Drug Identity
Active Ingredient
Divalproex Sodium
Chemical Class
Valproic Acid
Pharmacological Group
on the basis of mechanism of action
What is Epival Cr?
Uses
Sodium Valproate is anticonvulsant drug. It acts by potentiating GABA , an inhibitory neurotransmitter. Sodium Valproate is a drug of cho...
How It Works
Chemical Class
Valproic Acid
Pharmacological Group
on the basis of mechanism of action
Sodium Valproate also known as Divalproex Sodium. It is of Synthetic origin and belongs to Valproic Acid. It belongs to Na-Channel Antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Sodium Valproate is 144.20. Its pKa is 4.95.
How to Take It
1
Adult · PO
1 to 2 g — 12 hourly
As maintenance dose.
2
Adult · PO
600 mg — As recommended.
should be given in two divided doses. Take after food as starting dose. Increase gradually to maintenance dose.
3
Child · Oral
20 to 30 mg/kg — 24 hourly
Maintenance doses , exceed upto 35mg/kg
4
Child · Oral
0 to 400 mg — 24 hourly
initial daily dose for children weighing more than 20 kg ,should be given in two divided doses
5
Child · Oral
20 to 40 mg/kg — 24 hourly
initial daily dose for children weighing less han 20 kg ,should be given in two divided doses
6
Child · Slow IV
10 to 30 mg/kg — As recommended.
over 3-5 minutes, maximum upto 2.5g,
Safety Alerts
Sodium Valproate
Important Warnings
Sodium valporate should be used with caution in patients with liver disease, bleeding disorder, history of a brain disorder or any allergy
It should be used caution while driving motor vehicles or performing tasks that require alertness
Before having surgery, including dental surgery, inform the doctor about the use of drug
This may interfere with urine ketone testing and give false positive results, if very high sugar readings (e
Over 300) are occurring, ketones may be present in urine, contact the doctor or pharmacist
It should be used with extreme caution in children under 2 years old as serious liver problems exist
The drug is not recommended for use during pregnancy or lactation, Because it may cause some neural tube defect
Avoid use in pancreatitis, porphyria
Side Effects
The severe or irreversible adverse effects of Sodium Valproatewhich give rise to further complications include Thrombocytopenia. Sodium Valproate produces potentially life-threatening effects which include PancreatitisLiver damageExtrapyramidal symptomsHyperammonemia. which are responsible for the discontinuation of Sodium Valproate therapy. The signs and symptoms that are produced after the acute overdosage of Sodium Valproate include DeathDeepening coma. The symptomatic adverse reactions produced by Sodium Valproate are more or less tolerable and if they become severethey can be treated symptomaticallythese include Weight gainTremorHair lossGI disordersHematological disorderLeucopeniabone marrow depressionnocturnal enuresis
Drug Interactions
Sodium Valproate is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAspirinCarbamazepineErythromycinEthosuximideEthosuximideFosphenytoinLamotrigineMefloquine (HCl)MeropenemMethotrexatePhenobarbitonePhenytoin (Na)PrimidoneWarfarin (Na) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
Tab, Syrup Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 278.9
DVAGO observed price · per pack of 10 · as of 30 July 2026
Rs 27.89 per unit
Prices across sources
DRAPper pack of 50Rs 1,540.29
DVAGOper pack of 10Rs 278.9
Should you consider an alternative?
Other options containing Divalproex Sodium, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
Often Bought Together
Lalap — Lalap Tablets 100Mg (1 Strip = 7 Tablets)Rs 365.75Lalap — Lalap 10Mg/Ml Syrup 100Ml 1SRs 630.8Brivera — Brivera Tablets 100Mg (1 Box = 14 Tablets)Rs 1,030.75Ozamide — Ozamide Tablets 100Mg (1 Box = 2 Strips) (1 Strip = 7 Tablets)Rs 759.08Lalap — Lalap Tablets 50Mg (1 Strip = 7 Tablets)Rs 232.75
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