Drug Identity
Active Ingredient
Fluoxetine
Chemical Class
Propylamine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
N06AB03
Status
Essential Medicine
What is Fair?
Uses
Fluoxetine (HCl) is the prototype of antidepressant drug that selectively inhibits serotonin reuptake. Selective serotonin reuptake inhib...
How It Works
Chemical Class
Propylamine
Pharmacological Group
on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant pharmacological group
Fluoxetine is the derivative of Fluoxetine (HCl). It is of Synthetic origin and belongs to Propylamine. It belongs to Amine uptake inhibitor pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant pharmacological group. The Molecular Weight of Fluoxetine (HCl) is 345.80.
How to Take It
1
Adult · PO
20 to 80 mg — 24 hourly
If inadequate response, increase the dose no more often than every month by 10-20 mg/kg/day to a maximum of 80 mg/day.
2
Child
Not recommended in this age group
Safety Alerts
Fluoxetine (HCl) is contraindicated in conditions like Renal failure, Hypersensitivity, Breastfeeding
Important Warnings
Patient should observe caution while driving or performing other task requiring alertness because it may produce dizziness
Fluoxetine should be used with caution in patient with history of seizures, in kidney or liver impairment, with diseases or conditions that could effect metabolism or hemodynamic response
Side Effects
The severe or irreversible adverse effects of Fluoxetine (HCl)which give rise to further complications include Serum sicknessVasculitisSeizuresExtrapyramidal symptomsSinus bradycardiaManiaAltered platelet functionHypersensitivity pneumonitisLeukocytoclastic vasculitis. The signs and symptoms that are produced after the acute overdosage of Fluoxetine (HCl) include NauseaVomitingGrand Mal Seizures (epilepsy)AgitationRestlessnessHypomania
Drug Interactions
Fluoxetine (HCl) is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAdinazolamAlcoholAlprazolamFluoxetine reduces the clearance of alprazolamAtomoxetine HClThe effect and toxicity of atomoxetine could be increased by CYP2D6 inhibitor.Bupropion (HCl)CarbamazepinePlasma concentration of Carbamazepine increased by Fluvoxamine.MajorClarithromycinClomipramine (HCl)ClozapineFluoxetin increases the srum level of clozapine upto 76% by inhibiting its hepatic metabolism.ModerateDose of clozapine should be reduced if necessary.Close clinical monitoring is advised.DextromethorphanDiazepamfluoxetine prolong the half life of diazepamDigitoxinDigoxinSerum concentration of digoxin may increased by fluoxetine.MinorIf interaction occur dose adjustment is needed.EscitalopramContraindicatedFosphenytoinHaloperidolfluoxetine increase plasma concentration of haloperidoliloperidonecan inhibit iloperidone elimination and cause increased blood levels.Iloperidone doses should be reduced by one-half when administered with fluoxetineInsulin GlulisineFluoxetine (HCl)
oral antidiabetic products
pramlintide
ACE inhibitors
fibrates
monoamine oxidase inhibitors
salicylates
Storage
Caps, Soln Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 465.65
DRAP approved maximum price · per pack of 10 · approved 04 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 10Rs 465.65
Should you consider an alternative?
Other options containing Fluoxetine, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Futine
20Mg
Rs 323Rs 16.15/unit
Lowest price per unitWILSHIRE LABORATORIES
Reset
20mg
Rs 195.1Rs 19.51/unit
No DRAP alertsRITE PHARMA
Prozyn
20mg
Rs 204.3Rs 20.43/unit
Below approved ceilingPLATINUM PHARMACEUTICAL
Depex
20Mg
Rs 258Rs 25.8/unit
Below approved ceilingNo DRAP alertsMartin Dow Marker
Vonder
20mg
Rs 261.3Rs 26.13/unit
Below approved ceilingSTANDPHARM PAKISTAN
Flux
20Mg
Rs 407.54Rs 29.11/unit
HILTON PHARMA
Oxetin
20mg
Rs 427Rs 30.5/unit
Below approved ceilingNo DRAP alertsPHARMATEC PAKISTAN (PVT) LTD.
Depricap
20Mg
Rs 949.2Rs 31.64/unit
Below approved ceilingNABIQASIM INDUSTRIES
Prozac
20mg
Rs 995.54Rs 71.11/unit
No DRAP alertsELI LILLY PAKISTAN PVT LTD.
Oxecam
20mg
Rs 119.8
No DRAP alertsVALOR PHARMACEUTICALS
Fluotine
20mg
Rs 134.24
No DRAP alertsMEDERA PHARMACEUTICALS (PVT) LTD.
Phloxetin
20mg
Rs 130.21 ceiling
No DRAP alertsW.WOODWARD PAKISTAN (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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