Drug Identity
Active Ingredient
Fludarabine
Drug Class
Antineoplastics
ATC Code
L01BB05
Status
Essential Medicine
What is Fludara?
Uses
Fludarabine is used to treat B-cell chronic lymphocytic leukemia (CLL). Fludarabine is usually given after other treatments have failed. ...
How It Works
Administer over 15-30 min or continuous infusion. Reconstitute vials with SWFI, NS, or D5W to a concentration of 10-25 mg/ml. Standard IV dilution: 50-100 ml D5W or NS.
How to Take It
1
Adult · Slow IV
25 mg/ sq.meter — As recommended.
For 5 days
Safety Alerts
Haemolytic anaemia
Important Warnings
Use with caution in renal insufficiency, fever, documented infection or pre-existing hematological disorder or CNS disorders or peripheral neuropathy
Increased susceptibility to skin cancer, worsening of existing skin cancer
Side Effects
Acutemyeloidleukaemiaanorexiachillscoughdiarrhoeafeverimmunosuppressionmalaisemyelodysplastic syndromemyelosupressionoedemaperipheral neuropathypneumoniarash
Drug Interactions
Pentostatin
ethanol.
Pregnancy & Lactation
Pregnancy
Positive evidence of risk: Avoid
Lactation
Contraindicated. Discontinue breast-feeding.
Storage
Inj (reconstituted soln) Store in refrigerator. Use within 8 hrs if kept at room temperature.
Price Intelligence
Rs 124,754.64
DRAP approved maximum price · per pack of 5 · approved 01 Jul, 2024
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 5Rs 124,754.64
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