Drug Identity
Active Ingredient
Gentamicin
Drug Class
Aminoglycoside Antibacterials
ATC Code
D06AX07, J01GB03, S01AA11, S02AA14, S03AA06
Status
Essential Medicine
What is Gentamicin?
Uses
Gentamicin is an antibiotic that fights bacteria. Gentamicin is used to treat severe or serious bacterial infections. Gentamicin may also...
How It Works
Administer by deep IM route if possible. Slower absorption and lower peak concentrations, probably due to poor circulation in the atrophic muscle, may occur following IM injection; in paralysed patients, suggest IV route. Administer other antibiotics at least 1 hour before or 1 hour after gentamicin.
How to Take It
1
Adult · Intra Thecal
4 to 8 mg — As recommended.
As Required
2
Adult · IV,IM
3 to 5 mg/kg — As recommended.
In 3-4 divided doses for 7-10 days. Doses vary according to indication.
3
Adult · Otic
0.3 % — 6 hourly
1-2 drops
4
Adult · PO
1.5 mg/kg/dose — As recommended.
For prevention of becterial endocarditis. NOT to exceed 80 mg with ampicillin (1-2g). 30 minutes prior to procedures.
5
Adult · Topical
0.3 % — 8 hourly
Or twice a day if needed.
6
Adult
Scraped Dose
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. Gentamicin is usually given for 7 to 10 days. Gentamicin is i
7
Child · Ear
0.3 % — 6 hourly
-
8
Child · Intra Muscular
2 to 1.5 mg/kg — 8 hourly
9
Child · Intra Venous
2.5 mg/kg — 8 hourly
-
10
Child · Opthalmic
0.3 % — 6 hourly
-
11
Child · Topical
0.3 % — 6 hourly
-
Safety Alerts
Myasthenia gravis (aminoglycosides may impair neuromuscular transmission)
Important Warnings
To avoid excessive dosage in obese patients, use ideal weight for height to calculate dose and monitor serum amikacin concentration closely
Care must be taken with dosage, caution in conditions characterized by muscular weakness (aminoglycosides may impair neuromuscular transmission), renal impairment, infants, elderly, obesity
Ensure adequate hydration
if possible, dehydration should be corrected before starting an aminoglycoside, if possible, parenteral treatment should not exceed 7 days
Monitor serum levels as vestibular toxicity and nephrotoxicity may occur if serum levels exceed 10 microgram/ ml
Side Effects
Auditory damageimpaired neuromuscular transmissionirreversible ototoxicitynephrotoxicitysigns of liver dysfuncttransient myasthenic syndrome in patients with normal neuromuscular function with large doses given during surgeryvestibular damage. Rare: Antibiotic-associated colitiselectrolyte disturbanceshypocalcaemiahypokalaemiahypomagnesaemia on prolonged therapynauseaperipheral neuropathystomatitisvomiting
Drug Interactions
Neuromuscular blocking drugs
anaesthetic
ethacrynic acid
furosemide.
Pregnancy & Lactation
Pregnancy
Avoid, use only when no safer alternative available
Lactation
Caution advised, avoid
Storage
Inj, Eye Drops, Skin Oint or Cream Store at room temperature, Below 30°C. Do not Freeze.
Price Intelligence
Rs 123.44
DRAP approved maximum price · 5'sx2ml · approved 01 Jul, 2024
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
No retail prices recorded
Should you consider an alternative?
Other options containing Gentamicin, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Gentamycin
40mg
Rs 46.75
No DRAP alertsMEHRAN TRADERS
Cingentaampoule
20mg
Rs 79.54
BIO LABS (PVT) LTD.
Genzy
40mg
Rs 110.8
No DRAP alertsAKSON PHARMACEUTICALS (PVT) LTD.
Cingentaampoule
80mg
Rs 157.57
BIO LABS (PVT) LTD.
Cingentaampoule
40mg
Rs 435.2
BIO LABS (PVT) LTD.
GLYCOCIN
40mg
Rs 116.49 ceiling
No DRAP alertsMaxitech Pharma (Pvt) Ltd.
GLYCOCIN
80mg
Rs 155.32 ceiling
No DRAP alertsMaxitech Pharma (Pvt) Ltd.
GLYCOCIN
20mg
Rs 77.66 ceiling
No DRAP alertsMaxitech Pharma (Pvt) Ltd.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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