Drug Identity
Active Ingredient
Glibenclamide
Drug Class
Blood Glucose Lowering Drugs, Excluding Insulin
Chemical Class
Sulphonylurea
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
A10BB01
Status
Essential Medicine
What is Glucovance?
Uses
Glibenclamide is a oral hypoglycemic agent. Glibenclamide is used in the treatment of non-insulin dependent diabetes. Glibenclamide is us...
How It Works
Chemical Class
Sulphonylurea
Pharmacological Group
on the basis of mechanism of action and also classified in Drugs Affecting Glucose Metabolism and Antidiabetic Agent, Sulfonylurea pharmacological group
Glibenclamide also known as Glyburide. It is of Synthetic origin and belongs to Sulphonylurea. It belongs to Cyclo-oxygenase inhibitor pharmacological group on the basis of mechanism of action and also classified in Drugs Affecting Glucose Metabolism and Antidiabetic Agent, Sulfonylurea pharmacological group. The Molecular Weight of Glibenclamide is 494.00. Its pKa is 5.3.
How to Take It
1
Adult · PO
2.5 mg — 24 hourly
Dose may be increased by 2.5 mg.
2
Child
Not recommended in this age group
Safety Alerts
Renal dysfunction, congestive heart failure, acute diabetic ketoacidosis, metabolic acidosis, diabetic coma, Suspend therapy during surgery & clinical investigations using IV-iodinated contrast media
Important Warnings
Renal insufficiency, hepatic disease, concomitant medications that may affect renal function or result in significant haemodynamic change or may interfere with the disposition of metformin
Monitor haematologic parameters annually
Decreases vit 812 absorption, serum vit B12 measurements at 2 to 3 years interval is required
Side Effects
Nauseavomitingdiarrhoeaabdominal painloss of appetitecrises of hepatic porphyria & porphyria cutaneaelevations of se-rum urea &creatinine conc. Transient visual disturbancesLeukopeniathrombocytopeniapruritus urticariamaculopapular rash. Rare: Agranulocytosishaemolyticanaemiabone marrow aplasia & pancytopenialactic acidosis
Drug Interactions
Iodinated contrast media
alcohol
Thiazide & other diuretics
corti-costeroids
phenothiazines
thyroid products
oestrogens
oral contraceptives
Pregnancy & Lactation
Pregnancy
Risk cannot be ruled out.
Lactation
Contraindicated or not recommended.
Storage
Store Below 20°C. Tab Store in a well closed container, Below 40°C.
Price Intelligence
Rs 140.1
DVAGO observed price · per pack of 15 · as of 30 July 2026
Rs 9.34 per unit
No approved ceiling matched to this exact pack and strength.
Prices across sources
DVAGOper pack of 15Rs 140.1
ServaidRs 113.4
Should you consider an alternative?
Other options containing Glibenclamide, and what they are not.You pay Rs 102 more than the cheapest equivalent
Identical active ingredient at the same strength. Cheapest per unit first.
Glucomet
500mg
Rs 38Rs 3.8/unit
Lowest price per unitNo DRAP alertsPHARMATEC PAKISTAN (PVT) LTD.
Glucomet Plus
500mg
Rs 66.3Rs 6.63/unit
No DRAP alertsPHARMATEC PAKISTAN (PVT) LTD.
Glimet
500mg
Rs 77Rs 7.7/unit
No DRAP alertsC.C.L (PVT) LTD .
Glimetica
500mg
Rs 131.16 ceiling
Mega Pharmaceuticals limited
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
Often Bought Together
Getzid Mr — Getzid Mr Tablets 60Mg (1 Strip = 10 Tablets)Rs 190Empaa-M — Empaa-M Tablets 12.5Mg+500Mg (1 Strip = 7 Tablets)Rs 252.7Erlina — Erlina Tablets 10Mg/5Mg (1 Strip = 7 Tablets)Rs 272.65Erlina — Erlina Tablets 25Mg/5Mg (1 Strip = 7 Tablets)Rs 385.7Empator-M — Empator-M Tablets 12.5/500Mg (1 Strip = 7 Tablets)Rs 237.51
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