Drug Identity
Active Ingredient
Sulphamethoxazole
Drug Class
Sulfonamides And Trimethoprim
What is Hicot?
Uses
Sulphamethoxazole is antibacterial sulfonamide. Sulphamethoxazole is classified as an intermediate-acting sulfonamide and is longer-actin...
How It Works
Infuse over 60-90 min, must dilute well before giving. May be given less diluted in a central line. Not for IM injection. Maintain adequate fluid intake to prevent crystalluria. Administer around-the-clock every 6-12 hours.
How to Take It
1
Adult · PO
800 mg — 12 hourly
In Combination with trimethoprim 160 mg/day.
2
Child · Oral
25 to 30 mg/kg — 12 hourly
Maintenance, As required
3
Child · Oral
50 to 60 mg/kg — 24 hourly
Initial
Safety Alerts
Neonates, severe renal or hepatic insufficiency, blood dyscrasias
Important Warnings
Avoid in blood disorders, avoid in infants under 6 weeks (except for treatment or prophylaxis of pneumocystis pneumonia) because of the risk of kernicterus, elderly, G6PD deficiency (risk of haemolytic anaemia), maintain adequate fluid intake, predisposition to folate deficiency, predisposition to hyperkalaemia (in adults), hepatic and renal impairment (reduce or space out dosage), severe allergy or asthma, perform regular haematological tests during long term therapy
Discontinue if rash develops
Side Effects
Abdominal discomfortdiarrhoeaheadacheHyperkalaemianausearashvomitingglossitisblood dyscrasiasfolate deficiencyliver changes. Rarely: erythema multiformeLyell syndromeexfoliative dermatitisStevens-Johnson syndromeconvulsions
Drug Interactions
Folate inhibitors
anticoagulants
anticonvulsants
hypoglycaemics
cyclosporin
procainamide
aman-tadine
lamivudine
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Contraindicated or not recommended.
Storage
Inj Store at room temperature. Do not Freeze. Protect from Sunlight. Tab, Susp Store at room temperature. Protect from Sunlight and Moisture.
Price Intelligence
Rs 34.6
DRAP approved maximum price · per 50ml · approved 04 Nov, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper 50mlRs 34.6
Should you consider an alternative?
Other options containing Sulphamethoxazole, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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