Drug Identity
Active Ingredient
Ifosfamide
Drug Class
Antineoplastics
ATC Code
L01AA06
Status
Essential Medicine
What is Ifosfamin?
Uses
Ifosfamide is used with other medicines to treat testicular cancer in men. Ifosfamide is usually given after other treatments have failed...
How It Works
Administer slow IVP, IVP Bolus over 30 min to several hours or continuous IV infusion over 5 days. Dilute powder with SWFI or NS to a conc of 50 mg/ml. Further dilution in 50-100 ml D5W or NS is recommended for IV Infusion.
How to Take It
1
Adult · IV
5 to 8 g/ sq.meter — As recommended.
3-4 times in a week
2
Child · Intra Venous
1200 to 1800 mg/sq.meter — 24 hourly
For 5 Days, every 21-28 day cycle
Safety Alerts
Severe bone marrow suppression, acute infection, urinary-tract infection, urinary-tract obstruction, urothelial damage
Important Warnings
Impaired renal function, compromised bone marrow function, avoid in acute porphyrias, diabetes mellitus
Side Effects
Confusiondisorientationdrowsinesspsychosisrenal toxicity (may lead to tubular dysfunctionFanconis syndromeor diabetes insipidus)restlessnessurothelial toxicitysevere encephalopathyacute pancreatitisalopeciaarrhythmiasbone-marrow suppressionextravasation
Drug Interactions
Phenobarbital
carbamazepine
phenytoin.
Pregnancy & Lactation
Pregnancy
Positive evidence of risk: Avoid
Lactation
Contraindicated. Discontinue breast-feeding
Storage
Inj Store Below 30°C.
Price Intelligence
Price not recorded
No observed retail price and no approved ceiling matched to this pack.
Prices across sources
DRAPper unitRs 2,220.13
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