Drug Identity
Active Ingredient
Pyrimethamine
Drug Class
Antimalarials
Chemical Class
Sulphonamide
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Irene?
Uses
Sulfadoxine is antibacterial, belongs to Sulphonamide. Sulfadoxine is a long-acting drug with a very broad spectrum of activity Sulfadoxi...
How It Works
Chemical Class
Sulphonamide
Pharmacological Group
on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group
Sulfadoxine also known as sulphadoxine. It is of Synthetic origin and belongs to Sulphonamide. It belongs to Dihyropteroate synthetase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group. The Molecular Weight of Sulfadoxine is 310.30. Its pKa is 6.3.
How to Take It
1
Adult · PO
1500 mg — As recommended.
Single dose in combination with Pyrimethamine 75 mg.
2
Child · Oral
33.33 mg/kg — As recommended.
For Once, Dose for Paeds of 4-12 Yrs.
Safety Alerts
Severe liver or kidney dysfunction, Sulphonamide sensitivity, blood dyscrasias, neonates
Important Warnings
Impaired renal or hepatic function, porphyria, psoriasis, severe gastrointestinal, neurological or blood disorders
Perform regular blood counts during long-term prophylaxis
Avoid excess sunlight exposure
Side Effects
Abdominal painheadachenauseaflushingskin rash (discontinue immediately)pharyngitis or pruritus occursGI distressblood dyscrasias. Rarely erythema multiformeStevens-Johnson syndromeLyells syndrome.
Drug Interactions
Folate inhibitors.
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Contraindicated or not recommended.
Storage
Tab Store Below 40°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 13.21
DRAP approved maximum price · per pack of 2 · approved 05 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 2Rs 13.21
Should you consider an alternative?
Other options containing Pyrimethamine, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Fansidar
500mg
Rs 4,097.41
Below approved ceilingNo DRAP alertsMartin Dow Limited
Maladar
500mg
Rs 1,561.81 ceiling
EFROZE CHEMICAL INDUSTRIES (PVT) LTD.
Falcicure
500mg
Rs 15.42 ceiling
S.J & G. Fazul Ellahie (pvt) limited.
Fadoprim
500mg
Rs 78.09 ceiling
No DRAP alertsZINTA PHARMACEUTICAL INDUSTRY
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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