Drug Identity
Active Ingredient
Isoniazid
Drug Class
Antimycobacterials (Antituberculosis)
Chemical Class
Hydrazine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
J04AC01
Status
Essential Medicine
What is Isoniazid?
Uses
Isoniazid is an antibiotic that fights bacteria. Isoniazid is used to treat and to prevent tuberculosis (TB). You may need to take other ...
How It Works
Chemical Class
Hydrazine
Pharmacological Group
on the basis of mechanism of action and also classified in Antitubercular Drug pharmacological group
Isoniazid also known as Isonicotinic Acid Hydrazide, It is of Synthetic origin and belongs to Hydrazine. It belongs to Antimycobacterial agent pharmacological group on the basis of mechanism of action and also classified in Antitubercular Drug pharmacological group. The Molecular Weight of Isoniazid is 137.14. Its pKa is 1.8, 3.5, 9.5.
How to Take It
1
Adult · PO
300 mg — 24 hourly
Give 30 min. before breakfast for 2 months.
2
Adult
Scraped Dose
Follow all directions on your prescription label. Do not take isoniazid in larger or smaller amounts or for longer than recommended. Take isoniazid on an empty stomach, at least 1 hour before or 2
3
Child · Intra Muscular
15 mg/kg — 24 hourly
Single Dose
4
Child · Intra Venous
10 mg/kg — 24 hourly
Single Dose
5
Child · Oral
10 mg/kg — 24 hourly
Single Dose
Safety Alerts
Patients with previous isoniazid associated hepatic injury or other severe adverse reactions with iso-niazid
Important Warnings
Patients with active chronic liver disease or severe renal dysfunction
Isoniazid crosses the placental barrier and passes into maternal breast milk, observe neonates, breast fed infants of isoniazid treated mothers for any evidence of adverse effects
Acute porphyrias, diabetes mellitus, epilepsy, history of psychosis, HIV infection, malnutrition, slow acetylator status
Side Effects
Peripheral neuropathyagranulocytosisaplastic anaemiablood disordersconstipationconvulsionsdifficulty with micturitiondry mouthfevergynaecomastiahaemolytic anaemiahearing loss (in patients with end-stage renal impairment)hyperglycaemiahyperreflexiahypersensitivity reactions
Drug Interactions
The effectiveness of isoniazid may be decreased when administered with corticosteroid. The effects of benzodiazepines may be increased. The hepatic toxicity of both isoniazid and/or rifampicin may be increased when administered concomitantly
Pregnancy & Lactation
Pregnancy
Caution advised, use only if potential benefit outweighs risk
Lactation
Caution advised
Storage
Oral Syrup, Inj Store at room temperature. Do not Freeze. Protect from Sunlight. Tab Store in a well closed container, Between 15°C-30°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 317.4
DRAP approved maximum price · per pack of 1000 · approved 27 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 1000Rs 317.4
Should you consider an alternative?
Other options containing Isoniazid, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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