Drug Identity
Active Ingredient
Metformin
Drug Class
Blood Glucose Lowering Drugs, Excluding Insulin
Chemical Class
Biguanide
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
A10BA02
Status
Essential Medicine
What is Janumet?
Uses
Metformin (HCl) is oral biguanide antidiabetic agent, introduced in 1950s. It reduces elevated blood glucose concentration in diabetic pa...
How It Works
Chemical Class
Biguanide
Pharmacological Group
on the basis of mechanism of action and also classified in Antidiabetic Agent, Biguanide pharmacological group
Metformin is the derivative of Metformin (HCl). It is of Synthetic origin and belongs to Biguanide. It belongs to Hypoglycemic pharmacological group on the basis of mechanism of action and also classified in Antidiabetic Agent, Biguanide pharmacological group. The Molecular Weight of Metformin (HCl) is 165.62. Its pKa is 11.5.
How to Take It
1
Adult · PO
500 to 3000 mg — 12 hourly
Frequency may be increased upto 3times/day, if needed. Gradually increase upto 2-3 g/day.
2
Child
Not recommended in this age group
Safety Alerts
Renal or hepatic impairment, diabetic ketoacidosis or pre-coma, cardiac or respiratory failure, recent MI, acute alcohol intoxication, alcoholism
Important Warnings
Assess risk factors for lactic acidosis
Monitor renal function at least annually
Discontinue for 48 hours before and after surgery and measure renal function before resuming therapy, Elderly
Side Effects
Serious hyper sensitivity reactions including anaphylaxis and Stevens-Johnson syndrome (discontinue)nausealactic acidosis (discontinue)hypoglycaemiaconstipationheadachediarrhoeavomiting.
Drug Interactions
Alcohol
cimetidine
iodinated contrast agents
glucocorticoids
ACE inhibitors
potent CYP3A4 inhibitors
digoxin
insulin
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Storage
Tab Store in a well closed container, Between 15°C-30°C. Protect from Moisture.
Price Intelligence
Rs 736.26
DVAGO observed price · as of 30 July 2026
No approved ceiling matched to this exact pack and strength.
Prices across sources
DVAGORs 736.26
Should you consider an alternative?
Other options containing Metformin, and what they are not.You pay Rs 550 more than the cheapest equivalent
Identical active ingredient at the same strength. Cheapest per unit first.
Sitanext
50mg
Rs 186.55
No DRAP alertsNext Pharmaceutical Products (Pvt.) Ltd
Glyziamet
50mg
Rs 228.13
No DRAP alertsAGP
Treviamet
50mg
Rs 249.13
GETZ PHARMA PAKISTAN (PVT) LTD.
Sitazan
50mg
Rs 251.72
No DRAP alertsCELL
Itaglipplus
50mg
Rs 272.51
SAMI
Gviam
50mg
Rs 273
No DRAP alertsGenix Pharma Private Limited
Sgliptinplus
50mg
Rs 275
No DRAP alertsBARRETT HODGSON
Glusimet
50mg
Rs 279.93
No DRAP alertsSCILIFE
Valeom
50mg
Rs 285
HORIZON
Neoglip
50mg
Rs 288.75
ATCO
Treviametxr
50mg
Rs 330.41
GETZ PHARMA PAKISTAN (PVT) LTD.
Juviamplus
50mg
Rs 360
Helix Pharma
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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