Drug Identity
Active Ingredient
Sitagliptin
Drug Class
Diabetes
Chemical Class
Biguanide
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Juvia-M Plus?
Uses
Metformin (HCl) is oral biguanide antidiabetic agent, introduced in 1950s. It reduces elevated blood glucose concentration in diabetic pa...
How It Works
Chemical Class
Biguanide
Pharmacological Group
on the basis of mechanism of action and also classified in Antidiabetic Agent, Biguanide pharmacological group
Metformin is the derivative of Metformin (HCl). It is of Synthetic origin and belongs to Biguanide. It belongs to Hypoglycemic pharmacological group on the basis of mechanism of action and also classified in Antidiabetic Agent, Biguanide pharmacological group. The Molecular Weight of Metformin (HCl) is 165.62. Its pKa is 11.5.
How to Take It
1
Adult · PO
500 to 3000 mg — 12 hourly
Frequency may be increased upto 3times/day, if needed. Gradually increase upto 2-3 g/day.
2
Child
Not recommended in this age group
Safety Alerts
Renal or hepatic impairment, diabetic ketoacidosis or pre-coma, cardiac or respiratory failure, recent MI, acute alcohol intoxication, alcoholism
Important Warnings
Assess risk factors for lactic acidosis
Monitor renal function at least annually
Discontinue for 48 hours before and after surgery and measure renal function before resuming therapy, Elderly
Side Effects
Serious hyper sensitivity reactions including anaphylaxis and Stevens-Johnson syndrome (discontinue)nausealactic acidosis (discontinue)hypoglycaemiaconstipationheadachediarrhoeavomiting.
Drug Interactions
Alcohol
cimetidine
iodinated contrast agents
glucocorticoids
ACE inhibitors
potent CYP3A4 inhibitors
digoxin
insulin
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Storage
Tab Store in a well closed container, Between 15°C-30°C. Protect from Moisture.
Price Intelligence
Rs 361
DVAGO observed price · per pack of 10 · as of 30 July 2026
Rs 36.1 per unit
No approved ceiling matched to this exact pack and strength.
Prices across sources
DVAGOper pack of 10Rs 361
Should you consider an alternative?
Other options containing Sitagliptin, and what they are not.You pay Rs 174 more than the cheapest equivalent
Identical active ingredient at the same strength. Cheapest per unit first.
Sitanext
50mg 500mg
Rs 186.55Rs 26.65/unit
Lowest price per unitNo DRAP alertsNEXT PHARMA
Valeom
50mg 500mg
Rs 285Rs 28.5/unit
HORIZON PHARMACEUTICALS
Glyziamet
50mg 500mg
Rs 228.13Rs 32.59/unit
No DRAP alertsAGP PHARMA
Treviamet
50mg 500mg
Rs 249.13Rs 35.59/unit
GETZ PHARMA PAKISTAN
Sitazan
50mg 500mg
Rs 251.72Rs 35.96/unit
No DRAP alertsCELL LABORATORIES PVT. LTD.
Itaglip Plus
50mg 500mg
Rs 258.86Rs 36.98/unit
SAMI PHARM (PVT) LTD.
S-Gliptin Plus
50Mg 500Mg
Rs 261.24Rs 37.32/unit
No DRAP alertsBARRETT HODGSON PAKISTAN
Glusimet
50Mg 500Mg
Rs 265.93Rs 37.99/unit
No DRAP alertsSCILIFE PHARMA (PVT) LTD
Gvia-M
50Mg 500Mg
Rs 266Rs 38/unit
No DRAP alertsGENIX PHARMA PRIVATE LIMITED
Treviamet
50Mg 500Mg
Rs 538.72Rs 38.48/unit
GETZ PHARMA PAKISTAN
Neoglip
50Mg 500Mg
Rs 274.33Rs 39.19/unit
ATCO LABORATORIES LIMITED
Treviamet-Xr
50Mg 500Mg
Rs 313.88Rs 44.84/unit
GETZ PHARMA PAKISTAN
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
Often Bought Together
Getzid Mr — Getzid Mr Tablets 60Mg (1 Strip = 10 Tablets)Rs 190Empaa-M — Empaa-M Tablets 12.5Mg+500Mg (1 Strip = 7 Tablets)Rs 252.7Erlina — Erlina Tablets 10Mg/5Mg (1 Strip = 7 Tablets)Rs 272.65Erlina — Erlina Tablets 25Mg/5Mg (1 Strip = 7 Tablets)Rs 385.7Empator-M — Empator-M Tablets 12.5/500Mg (1 Strip = 7 Tablets)Rs 237.51
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