Drug Identity
Active Ingredient
Ketamine
Chemical Class
Phenyl Cyclohexane
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
N01AX03
Status
Essential Medicine
What is Katromin?
Uses
Ketamine (HCl) non barbiturate, sedative hypnotic used parenterally to provide anaesthesia for short diagnostic and surgical procedures. ...
How It Works
Chemical Class
Phenyl Cyclohexane
Pharmacological Group
on the basis of mechanism of action and also classified in General Anesthetics pharmacological group
It is of Synthetic origin and belongs to Phenyl Cyclohexane. It belongs to N-methyl d-aspartate antagonist pharmacological group on the basis of mechanism of action and also classified in General Anesthetics pharmacological group. The Molecular Weight of Ketamine (HCl) is 274.20. Its pKa is 7.5.
How to Take It
1
Adult · IM
450 to 1000 mg — 24 hourly
2
Adult · IV
50 to 350 mg — 24 hourly
Slowly over 60 sec.
3
Adult
Scraped Dose
Fasting prior to induction of anesthesia or restraint with ketamine hydrochloride is not essential; however, when preparing for elective surgery, it is advisable to withhold food for at least six h
4
Child · Intra Muscular
3 to 7 mg/kg — As recommended.
As Required
5
Child · Intravenous
0.5 to 2 mg/kg — As recommended.
As required
Safety Alerts
Ketamine (HCl) is contraindicated in conditions like Angina, Hypertension, Myocardial infarction, Psychiatric disease, Raised intracranial pressure, Eclampsia, Acne rosacea
Important Warnings
Do not administer ketamine alone in case of surgery or diagnostic procedures of pharynx, larynx
Avoid use in patients with hypertension and history of cerebrovascular accident or increase intraocular pressure
It should be used with caution in patients with elevated CSF pressure
It should be used with caution in chronic alcoholic and acutely alcohol intoxicated patients
Do not drive, operate hazardous machinery for 24 hrs
or more after taking drug
It should be avoided in patients prone to hallucinations & psychotic disorders
Side Effects
The severe or irreversible adverse effects of Ketamine (HCl)which give rise to further complications include Sinus tachycardiaHallucinationsHypotensionMaculopapular rashHypertensionSinus bradycardiaRespiratory depressionLaryngospasm. The symptomatic adverse reactions produced by Ketamine (HCl) are more or less tolerable and if they become severethey can be treated symptomaticallythese include NauseaVomitingAnorexiaSkin rashesDiplopia
Drug Interactions
Ketamine (HCl) is known to interact with other drugs
the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholAminophyllineEnfluraneErgometrine (Maleate)EtherHalothaneHalothaneMemantineMidazolamPancuronium (Br)PropiomazineConcurrent use of ketamine
especially in high doses or when rapidly administered
with propiomazine may increase the risk of hypotension or respiratory depression.Thyroxine (Na)Vecuronium (Br)VORICONAZOLEVoriconazole may increase the serum concentration of ketamine by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Storage
IV Inj, IV Inf, IM Inj Store at room temperature, Below 30°C. Do not Freeze. Protect from Sunlight.
Price Intelligence
Rs 43.33
DRAP approved maximum price · per unit · approved 01 Jul, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper unitRs 43.33
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Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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