Drug Identity
Active Ingredient
Chlorpheniramine
Chemical Class
Alkaloid
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Kofnil?
Uses
Brompheniramine and pseudoephedrine is a combination medicine used to treat symptoms of the common cold or seasonal allergies, including ...
How It Works
Chemical Class
Alkaloid
Pharmacological Group
on the basis of mechanism of action and also classified in Nasal Decongestants pharmacological group
Pseudoephedrine are the derivatives of Pseudoephedrine (HCl). It is of Natural origin and belongs to Alkaloid. It belongs to Alpha & Beta adrenergic agonist pharmacological group on the basis of mechanism of action and also classified in Nasal Decongestants pharmacological group. The Molecular Weight of Pseudoephedrine (HCl) is 201.70. Its pKa is 9.22.
How to Take It
1
Adult · PO
60 to 240 mg — 4 hourly
2
Adult · PO
120 mg — 2 hourly
3
Adult
Scraped Dose
Use exactly as directed on the label, or as prescribed by your doctor. You should not use antihistamine medication to make a child sleepy. Measure liquid medicine with the supplied measuring device
4
Child · Oral
1.5 mg/kg — 8 hourly
-
Safety Alerts
Do not use brompheniramine and pseudoephedrine if you have taken an MAO inhibitor in the past 14 days
A dangerous drug interaction could occur
MAO inhibitors include isocarboxazid , linezolid , phenelzine , rasagiline , selegiline , and tranylcypromine
You should not use this medication if you are allergic to brompheniramine or pseudoephedrine
Ask a doctor or pharmacist if it is safe for you to take this medicine if you have: a breathing problem such as emphysema or chronic bronchitis
Important Warnings
Follow all directions on the label and package
Use exactly as directed
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hivesdifficult breathingswelling of your facelipstongueor throat. Brompheniramine and pseudoephedrine may cause serious side effects. Stop using brompheniramine and pseudoephedrine and call your doctor at once if you have: nervousnessdizzinessor sleeplessnesschest painfast or uneven heart ratelittle or no urinatingdangerously high blood pressure (severe headachebuzzing in your earsanxietyshortness of breath )
Drug Interactions
Using brompheniramine and pseudoephedrine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication
a sleeping pill
a muscle relaxer
or medicine for anxiety or seizures. Ask a doctor or pharmacist before using this medicine if you are also using any other drugs
including prescription and over-the-counter medicines
vitamins
and herbal products . Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.
Storage
Syrup Store in a well closed container, Below 30°C. Do not Freeze. Protect from Sunlight. Tab Store in a well closed container, Below 40°C. Protect from Sunlight.
Price Intelligence
Rs 82.89
DRAP approved maximum price · per pack of 100 · approved 23 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 100Rs 82.89
Should you consider an alternative?
Other options containing Chlorpheniramine, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Reltus C&F
Rs 81.5Rs 8.15/unit
No DRAP alertsPHARMATEC PAKISTAN (PVT) LTD.
Panadol Cf
Rs 95Rs 9.5/unit
HALEON
Reltus C&F
100ml
Rs 172.43Rs 172.43/unit
No DRAP alertsPHARMATEC PAKISTAN (PVT) LTD.
Cofcol Elixir
120Ml
Rs 285Rs 285/unit
No DRAP alertsABBOTT LABORATORIES (PAK) LTD
Cofcolelixir
90ml
Rs 55
No DRAP alertsAbbot Laboratories (Pak) Ltd
Pulmonolcf
Rs 345
No DRAP alertsC.C.L (Pvt) Ltd .
Tylolcf
Rs 345
DON VALLEY PHARMACEUTICALS (PVT) LTD.
Pedrolcf
4mg
Rs 561.11
No DRAP alertsSTANLEY PHARMACEUTICALS (PVT) LTD.
Pedrol CF
500mg
Rs 561.11 ceiling
No DRAP alertsSTANLEY PHARMACEUTICALS (PVT) LTD.
Tyladol CF
500mg
Rs 517.26 ceiling
No DRAP alertsBRYON PHARMACEUTICALS (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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