Drug Identity
Active Ingredient
Hydrochlorothiazide
Drug Class
Angiotensin-Ii Antagonists, Combinations
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C03AA03
Status
Essential Medicine
What is Kosartdiu?
Uses
Hydrochlorothiazide is a prototype drug of thiazide diuretics. Hydrochlorothiazide is antihypertensive agent. It increases the urination ...
How It Works
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group
It is of Synthetic origin and belongs to Thiazide. It belongs to NaCl cotransport inhibitor pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group. The Molecular Weight of Hydrochlorothiazide is 297.74. Its pKa is 7.9, 9.2.
How to Take It
1
Adult · PO
25 to 100 mg — 24 hourly
As Required
2
Child · Oral
2.5 mg/kg — 12 hourly
Safety Alerts
Hepatic impairment, anuria, moderate to severe renal impairment, dialysis, intravascular volume depletion
Important Warnings
Hepatic impairment, renal impairment, intravascular volume depletion, renal artery stenosis, obstructive valvular disease, aortic stenosis, outflow obstruction, cardiomyopathy, SLE, gout, obstructive valvular disease
Monitor serum electrolytes
Side Effects
Hyperkalaemiaangioedemasymptomatic hypotension including dizziness particularly in patients with intravascular volume depletione.g. those taking high-dose diureticsarthralgiarhinitisflatulenceorthostatic effectsdiarrhoealiver function abnormalitiesmyalgiahypertriglyceridaemiamigraineurticariapruritus
Drug Interactions
Barbiturates
narcotics
antidiabetic agents
cholestyramine
colestipol
corticosteroids
ACTH
adrenaline
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Storage
Store in a well closed container, at room temperature. Protect from Moisture and Heat. Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 570.18
DRAP approved maximum price · per pack of 20 · approved 04 Sep, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 20Rs 570.18
Should you consider an alternative?
Other options containing Hydrochlorothiazide, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Diuza
25mg
Rs 45.3Rs 1.51/unit
Below approved ceilingZAFA PHARMACEUTICAL LAB
Normopress
25mg
Rs 95
Below approved ceilingNo DRAP alertsCCL Pharmaceuticals (Pvt.) Ltd.
Bepsar
25Mg
Rs 101.5Rs 10.15/unit
Below approved ceilingNABIQASIM INDUSTRIES
Qsartan
25Mg
Rs 116.9Rs 11.69/unit
Below approved ceilingHIGH-Q INTERNATIONAL.
A2a
25Mg
Rs 144.2Rs 14.42/unit
Below approved ceilingWILSONS PHARMACEUTICALS
Xavor
25mg
Rs 146.6Rs 14.66/unit
Below approved ceilingNo DRAP alertsFEROZSONS LABORATORIES
Normopress
50mg
Rs 150
Below approved ceilingNo DRAP alertsCCL Pharmaceuticals (Pvt.) Ltd.
Normozide
12.5mg
Rs 155
No DRAP alertsCCL Pharmaceuticals (Pvt.) Ltd. DML: 000052
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
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brands
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