Drug Identity
Active Ingredient
Spironolactone
Chemical Class
Steroid
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C03DA01
Status
Essential Medicine
What is Lactonar?
Uses
Spironolactone is a potassium-sparing diuretic (water pill) that prevents your body from absorbing too much salt and keeps your potassium...
How It Works
Chemical Class
Steroid
Pharmacological Group
on the basis of mechanism of action and also classified in Diuretic Potassium Sparing pharmacological group
It is of Synthetic origin and belongs to Steroid. It belongs to Aldosterone antagonist pharmacological group on the basis of mechanism of action and also classified in Diuretic Potassium Sparing pharmacological group. The Molecular Weight of Spironolactone is 416.57. Its pKa is not relevant.
How to Take It
1
Adult · PO
50 to 100 mg — 24 hourly
2
Adult
Scraped Dose
Take spironolactone exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change
3
Child · Oral
1 to 1.5 mg/kg — 12 hourly
-
Safety Alerts
You should not use spironolactone if you are allergic to it, or if you have: Addison's disease (an adrenal gland disorder)
high levels of potassium in your blood ( hyperkalemia )
if you are unable to urinate
or if you are also taking eplerenone
To make sure spironolactone is safe for you, tell your doctor if you have: an electrolyte imbalance (such as low levels of calcium, magnesium, or sodium in your blood)
Important Warnings
You should use spironolactone with caution if you have kidney problems, high levels of potassium in your blood, Addison's disease , if you are unable to urinate, or if you are also taking eplerenone
Spironolactone has caused tumors in animals but it is not known whether this could occur in people
Do not use this medicine for any condition that has not been checked by your doctor
Side Effects
Get emergency medical help if you have signs of an allergic reaction to spironolactone: hivesdifficulty breathingswelling of your facelipstongueor throat. Call your doctor at once if you have: a light-headed feelinglike you might pass outlittle or no urinationhigh potassium level - nauseaweaknesstingly feelingchest painirregular heartbeatsloss of movemento signs of other electrolyte imbalances - increased thirst or urination
Drug Interactions
Using spironolactone with other drugs that make you dizzy can worsen this effect. Ask your doctor before using opioid medication
a sleeping pill
a muscle relaxer
or medicine for anxiety
depression
or seizures . Tell your doctor about all your other medicines
especially: colchicine
digoxin
Storage
Tab Store in a well closed container, Below 40°C. Protect from Sunlight.
Price Intelligence
Rs 218.73
DRAP approved maximum price · per pack of 100 · approved 04 Nov, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 100Rs 218.73
Should you consider an alternative?
Other options containing Spironolactone, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Aldactone-A
25mg
Rs 620Rs 6.2/unit
Lowest price per unitSEARLE PAKISTAN (PVT) LTD.
Dobro
25mg
Rs 202.36 ceiling
No DRAP alertsSCOTMANN PHARMACEUTICALS
Spirodyn
25mg
Rs 307.49 ceiling
No DRAP alertsCCL Pharmaceuticals (Pvt.) Ltd.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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