Drug Identity
Active Ingredient
Rifampicin
Drug Class
General
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
J04AB02
Status
Essential Medicine
What is Lederrif?
Uses
Rifampicin belongs to the group of complex macrocyclic antibiotic. Rifampicin is a zwitterionic. Rifampicin results from a condensation r...
How It Works
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group
Rifampicin also known as Rifampin. It is of Synthetic origin and belongs to Rifamycin. It belongs to rRNA polymerase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group. The Molecular Weight of Rifampicin is 822.90. Its pKa is 1.7, 7.9.
How to Take It
1
Adult · PO
450 to 600 mg — As recommended.
In 2-4 div.doses. Maximum dose: 600mg. Give 30 min before breakfast. Duration may vary according to indication.
2
Child · Oral
10 to 20 mg/kg — 24 hourly
Max 60mg/day
Safety Alerts
Previous hypersensitivity to any rifamycin, Acute porphyrias, jaundice
Important Warnings
Caution patients against intentional or accidental interruption of daily dosage regimen for renal hypersensitivity reactions when therapy is resumed
Urine, faeces, saliva, sputum, sweat and tears may be coloured red-orange
Side Effects
Acute renal failureadrenal insufficiencyalterations of liver functionanorexiaantibiotic-associated colitisbody secretions coloured orange-redcollapse and shockdiarrhoeadisseminated intravascular coagulationDrowsinesseosinophiliaexfoliative dermatitisflushingGI symptomshaemolytic anaemia
Drug Interactions
Rifampicin induces hepatic enzymes which accelerate the metabolism of several drugs including oestrogens
corticosteroids
phenytoin
sulfonylureas
and
Pregnancy & Lactation
Pregnancy
Caution advised, use only if potential benefit outweighs risk
Lactation
Caution advised
Storage
Inj (reconstituted soln) Store at room temperature. Use within 24 hrs if kept at room temperature. Tab, Caps, Susp Store in a well closed container, Below 40°C. Protect from Sunlight, Moisture and Heat.
Price Intelligence
Rs 608.1
Servaid observed price · as of 30 July 2026
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 608.1
Should you consider an alternative?
Other options containing Rifampicin, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Mycosin
450mg
Rs 13.6
No DRAP alertsMS SIZA INTERNATIONAL PVT LTD.
Rimj
5ml
Rs 108.72
Global Pharmaceuticals Pvt Ltd
Rimabex
Rs 57.98 ceiling
CIBEX (PRIVATE) LIMITED
Werrick&#
100mg
Rs 52.79 ceiling
WERRICK PHARMACEUTICALS
Rifacin
150mg
Rs 1,047.37 ceiling
Pharmawise Labs. Private Limited
Rim-J
100mg
Rs 108.72 ceiling
Global Pharmaceuticals Pvt Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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