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Drug Identity
Active Ingredient
Hydrochlorothiazide
Drug Class
Cardiac Care
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
C03AA03
Status
Essential Medicine
What is Losarplus?
Uses
Hydrochlorothiazide is a prototype drug of thiazide diuretics. Hydrochlorothiazide is antihypertensive agent. It increases the urination ...
How It Works
Chemical Class
Thiazide
Pharmacological Group
on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group
It is of Synthetic origin and belongs to Thiazide. It belongs to NaCl cotransport inhibitor pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agent, Combination pharmacological group. The Molecular Weight of Hydrochlorothiazide is 297.74. Its pKa is 7.9, 9.2.
How to Take It
1
Adult · PO
25 to 100 mg — 24 hourly
As Required
2
Child · Oral
2.5 mg/kg — 12 hourly
Safety Alerts
Hepatic impairment, anuria, moderate to severe renal impairment, dialysis, intravascular volume depletion
Important Warnings
Hepatic impairment, renal impairment, intravascular volume depletion, renal artery stenosis, obstructive valvular disease, aortic stenosis, outflow obstruction, cardiomyopathy, SLE, gout, obstructive valvular disease
Monitor serum electrolytes
Side Effects
Hyperkalaemiaangioedemasymptomatic hypotension including dizziness particularly in patients with intravascular volume depletione.g. those taking high-dose diureticsarthralgiarhinitisflatulenceorthostatic effectsdiarrhoealiver function abnormalitiesmyalgiahypertriglyceridaemiamigraineurticariapruritus
Drug Interactions
Barbiturates
narcotics
antidiabetic agents
cholestyramine
colestipol
corticosteroids
ACTH
adrenaline
Pregnancy & Lactation
Pregnancy
Contraindicated in pregnancy.
Lactation
Not recommended.
Storage
Store in a well closed container, at room temperature. Protect from Moisture and Heat. Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 267.5
DVAGO observed price · as of 30 July 2026
Prices across sources
DVAGORs 267.5
DRAPper pack of 20Rs 599.3
Should you consider an alternative?
Other options containing Hydrochlorothiazide, and what they are not.You pay Rs 11 more than the cheapest equivalent
Identical active ingredient at the same strength. Cheapest per unit first.
Coa2A
50mg
Rs 256.5
WILSONS PHARMACEUTICALS
Xavordiu
50mg
Rs 274
No DRAP alertsFEROZSONS
Losaanh
50mg
Rs 346.8
MAPLE
Coeziday
50mg
Rs 510
Werrick Pharmaceuticals Pakistan
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
246
brands
220
molecules
1
alerts