Drug Identity
Active Ingredient
Nortriptyline
Drug Class
Antidepressants
Chemical Class
Amine
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Modrin?
depression and for the managemen...
used to treat depression and for the management of chronic, severe neurogenic pain
How It Works
Chemical Class
Amine
Pharmacological Group
on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant pharmacological group
It is of Synthetic origin and belongs to Amine. It belongs to Amine reuptake inhibitor pharmacological group on the basis of mechanism of action and also classified in Psychotherapeutic Drugs and Antidepressant pharmacological group. The Molecular Weight of Nortriptyline (HCl) is 299.80. Its pKa is 9.7.
How to Take It
1
Adult · PO
25 mg — 8 hourly
upto 150 mg/day . Frequency may be increased upto 4 times/day if needed.
2
Child
Not recommended in this age group
Safety Alerts
Severe cardiac insufficiency, comatose states, severe depression, pheochromocytoma, renal or hepatic failure, severe hepatic impairment, marked cerebral atherosclerosis, , blood dyscrasias, heart block, arrhythmias, mania, porphyria
Important Warnings
Epilepsy, liver, respiratory or cardiac disease, cardiac arrhythmias, thyrotoxicosis, elderly, glaucoma, hypothyroidism, myasthenia gravis, prostatic hypertrophy, Parkinsons disease
reduce dose or use anti-Parkinsonian drugs in patients showing extra-pyramidal reactions, concurrent ECT, hyperthyroidism, psychosis, suicidal tendencies, anaesthesia
Withdraw gradually
Side Effects
Acute dystonias and dyskinesiasakathisiahyperglycaemiaParkinsonismdrowsinessinsomniaagitationtachycardialeucopeniahyperprolactinaemiaarrhythmiasECG changeshypotensionanticholinergic effects (e.g.. dry monthblurred vision)
Drug Interactions
Adrenaline
alcohol
barbiturates
CNS depressants
other antipsychotics
anticholinergics
antacids
do-paminergics
Pregnancy & Lactation
Pregnancy
Avoid unless potential benefit outweighs risk
Lactation
Contraindicated, avoid
Storage
Caps Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture. Soln Store in a well closed container, Below 40°C. Do not Freeze. Protect from Sunlight and Moisture.
Price Intelligence
Rs 38
DVAGO observed price · as of 30 July 2026
Prices across sources
DVAGORs 38
ServaidRs 260
DRAPper pack of 100Rs 97.37
Should you consider an alternative?
Other options containing Nortriptyline, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Modecate
Rs 117.41
GLAXOSMITHKLINE
Flucate
Rs 128.37
AKHAI
Flucate
25mg
Rs 146.3Rs 146.3/unit
AKHAI PHARMA
Sensival
25mg
Rs 188.2Rs 9.41/unit
No DRAP alertsPHARMADIC
Motival
Rs 317
GLAXOSMITHKLINE
Motival
10mg 0.5mg
Rs 499Rs 4.99/unit
GlaxoSmithKline PAKISTAN
Motival
10mg
Rs 499
GLAXOSMITHKLINE
Mkate
25mg/ml
+ Flupenazinedecanoate
Rs 148.23
OPHTH-PHARMA (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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