Drug Identity
Active Ingredient
Pza 300 Mg
Drug Class
General
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
J04AK02
Status
Essential Medicine
What is Myrinp?
Uses
Rifampicin belongs to the group of complex macrocyclic antibiotic. Rifampicin is a zwitterionic. Rifampicin results from a condensation r...
How It Works
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group
Rifampicin also known as Rifampin. It is of Synthetic origin and belongs to Rifamycin. It belongs to rRNA polymerase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group. The Molecular Weight of Rifampicin is 822.90. Its pKa is 1.7, 7.9.
How to Take It
1
Adult · PO
450 to 600 mg — As recommended.
In 2-4 div.doses. Maximum dose: 600mg. Give 30 min before breakfast. Duration may vary according to indication.
2
Child · Oral
10 to 20 mg/kg — 24 hourly
Max 60mg/day
Safety Alerts
Liver disease, previous hypersensitivity to any rifamycin, patients with previous isoniazid associated hepatic injury or other severe adverse reactions with isoniazid, hypersensitivity to ethambutol, optic neuritis
Important Warnings
Patients with active chronic liver disease or severe renal dysfunction
Isoniazid crosses the placental barrier and passes into maternal breast milk, observe neonates, breast fed infants of isoniazid treated mothers for any evidence of adverse effects
Not recommended for intermittent therapy, caution patients against intentional or accidental interruption of daily dosage regimen, since rare renal hypersensitivity reactions have been reported when therapy is resumed
Urine, faeces, saliva, sputum, sweat and tears may be coloured red-orange
Reduce dosage in patients with decreased renal functions
Not recommended in children under thirteen years age
Perform frequently liver function tests and blood uric acid determinations, history of gout or diabetes
Withdraw treatment if liver damage or hyperuricaemia accompanied by acute gouty arthritis occurs
Side Effects
Anaphylactoid reactionsheartburnepigastric dis-tressanorexianauseavomitingdiarrhoeasore mouthrashpruritusurticariaeosinophiliathrombocytopeniamuscular weaknesspain in extremities
Drug Interactions
Probenecid
sulfinpyrazone
oral typhoid vaccine. Rifampicin induces hepatic microsomal enzymes that metabolize a wide variety of drugs e.g. metoprolol
propranolol
quinidine
corticosteroids
contra-ceptives
oral anticoagulants
Pregnancy & Lactation
Pregnancy
Risk cannot be ruled out.
Lactation
Caution advised or effect undetermined.
Storage
Inj (reconstituted soln) Store at room temperature. Use within 24 hrs if kept at room temperature. Tab, Caps, Susp Store in a well closed container, Below 40°C. Protect from Sunlight, Moisture and Heat.
Price Intelligence
Rs 1,818
Servaid observed price · as of 30 July 2026
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 1,818
DRAPper pack of 100Rs 3,397.92
Should you consider an alternative?
Other options containing Pza 300 Mg, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Mycosin
450mg
Rs 13.6
No DRAP alertsMS SIZA INTERNATIONAL PVT LTD.
Rimj
5ml
Rs 108.72
Global Pharmaceuticals Pvt Ltd
Pyrazid
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Rs 337.5
Below approved ceilingNo DRAP alertsSchazoo Zaka (Pvt) Ltd
Lederrif
300mg
Rs 364.2
ICI Pharmaceuticals Ltd
Lederrif
450mg
Rs 388.8
ICI Pharmaceuticals Ltd
Myambutol
400mg
Rs 475
Pfizer Laboratories (Pvt) Ltd.
Lederrif
600mg
Rs 608.1
ICI Pharmaceuticals Ltd
Rifin-E
150mg
Rs 822.4
Below approved ceilingPacific Pharmaceutical Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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