Drug Identity
Active Ingredient
Tobramycin
Drug Class
Aminoglycoside Antibacterials
ATC Code
J01GB01, S01AA12
Status
Essential Medicine
What is Nebcin?
Uses
Tobramycin is an aminoglycoside (ah-meen-oh-GLY-ko-side) antibiotic. Tobramycin fights infections that are caused by bacteria. Tobramycin...
How It Works
Infuse over 30-60 min. Give penicillins or cephalosporins at least 1 hour apart from tobramycin. Standard diluent dose/100 ml NS; minimum volume, 50 ml NS
How to Take It
1
Adult · IM,Slow IV
3 to 5 mg/ kg — As recommended.
In 3-4 divided doses.
2
Adult · Ophthalmic, Otic
0.3 % w/v — 6 hourly
3
Child · Intra Muscular
2 to 2.5 mg/kg — 8 hourly
-
4
Child · Intra Venous
2 to 2.5 mg/kg — 8 hourly
-
Safety Alerts
You should not use this medication if you are allergic to tobramycin or similar antibiotics (amikacin, gentamicin, kanamycin, neomycin, paromomycin , streptomycin )
To make sure tobramycin injection is safe for you, tell your doctor if you have: kidney disease
a muscle disorder such as myasthenia gravis
Parkinson's disease
or a metabolic disorder such as high or low levels of potassium, calcium, or magnesium in your blood
Important Warnings
To avoid excessive dosage in obese patients, use ideal weight for height to calculate dose and monitor serum amikacin concentration closely
Care must be taken with dosage, caution in conditions characterized by muscular weakness (aminoglycosides may impair neuromuscular transmission)
Ensure adequate hydration
if possible, dehydration should be corrected before starting an aminoglycoside, if possible, parenteral treatment should not exceed 7 days, renal impairment, auditory, vestibular or neuromuscular dysfunction, haemoptysis
Monitor auditory and renal function during therapy
Side Effects
Auditory damageimpaired neuromuscular transmissionirreversible ototoxicitynephrotoxicitytransient myasthenic syndrome in patients with normal neuromuscular function with large doses given during surgeryvestibular damage. Rare: Antibiotic-associated colitiselectrolyte disturbanceshypocalcaemiahypokalaemiahypomagnesaemia on prolonged therapynauseaperipheral neuropathystomatitisvomitingBlood disorders
Drug Interactions
Drugs with nephrotoxic or ototoxic potential
diu-retics
urea
anti cholinesterases
botulinum toxin.
Storage
Eye Drops, Oint, Inj Store at room temperature or refrigerator. Protect from Sunlight.
Price Intelligence
Rs 305.43
Servaid observed price · as of 30 July 2026
No approved ceiling matched to this exact pack and strength.
Prices across sources
ServaidRs 305.43
Should you consider an alternative?
Other options containing Tobramycin, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Obrexeye
5ml
+ Eye
Rs 121.83
No DRAP alertsVega Nutraceutecal
Eyebrexeyeoint
+ Eye
Rs 125.39
No DRAP alertsBarrett Hodgson Pakistan (Private) Ltd.
Tobracineyeeye
5ml
+ Eye
Rs 132
Helix Pharma
Nebraeyeoint
+ Eye
Rs 140.47
No DRAP alertsRemington Pharmaceuticals Industries
Eyebradexeyeoint
3.5g
+ Eye
Rs 150.09
No DRAP alertsBarrett Hodgson Pakistan (Private) Ltd.
Eyebrexeye
5ml
+ Eye
Rs 185.23
No DRAP alertsBarrett Hodgson Pakistan (Private) Ltd.
Eyebrex Eye
0.3% 5ml
+ Eye
Rs 190Rs 190/unit
No DRAP alertsBARRETT HODGSON PAKISTAN
Tobra Eye
5Ml
+ Eye
Rs 204.25Rs 204.25/unit
No DRAP alertsSCHAZOO PHARMACEUTICAL LAB
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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