1ml

Neopyrolate

NEO-PYROLATE

Neostigmine

Brookes Pharmaceutical Labs (Pvt) Ltd.

Drug Identity

Active Ingredient

Neostigmine

Drug Class

Pain Management

Chemical Class

Quaternary Ammonium

Pharmacological Group

on the basis of mechanism of action and also cl...

ATC Code

N07AA01, S01EB06

Status

Essential Medicine

What is Neopyrolate?

Uses

Neostigmine is used to reverse the effects of anesthesia medications used during surgery . Neostigmine may also be used for purposes not ...

How It Works

Chemical Class

Quaternary Ammonium

Pharmacological Group

on the basis of mechanism of action and also classified in Antidotes and Cholinergic Agonist pharmacological group

Neostigmine (Methylsulphate),are the derivatives of Neostigmine. It is of Synthetic origin and belongs to Quaternary Ammonium. It belongs to Cholinesterase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antidotes and Cholinergic Agonist pharmacological group. The Molecular Weight of Neostigmine is 223.30. It is weakly acidic drug, 4.98% solution of the drug is isotonic and Its pKa is 12.0.

How to Take It

Adult · IM

0.02 mg/ kg — As recommended.

For diagnosis of myasthenia gravis

Adult · IV, IM, SC

0.5 to 2.5 mg — As recommended.

Additional doses depend upon the patient response. Max. 10mg/day

Adult · PO

15 mg — 4 hourly

Max. 375mg/day

Child · Intra Venous

50 to 0 ug/kg — As recommended.

To severe neuromuscular blockade.

Child · Oral

200 to 0 mg/kg — 6 hourly

For Myasthenia grains.

Safety Alerts

Acute haemorrhage, ulcerative colitis, narrow-angle glaucoma, tachycardia, obstructive uropathy, paralytic ileus, obstructive disease of GI tract, myasthenia gravis, hypersensitivity to glycopyrrolate or any component of the formulation, intestinal or urinary obstruction

Important Warnings

Bronchial asthma, cardiac disease, vagotonia, epilepsy, Parkinsonism, elderly, patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis may predispose megacolon, hyperthyroidism, CAD, CHF, arrhythmias, tach-ycardia, BPH, hiatus hernia with reflux

Side Effects

Nauseavomitingdry skinconstipationdry throatdry mouthirritation at injection sitedry nosediaphoresis diarrhoea and abdominal cramp

Drug Interactions

Cyclopropane or halothane anaesthesia. Depo-larising muscle relaxants.

Pregnancy & Lactation

Pregnancy

Risk cannot be ruled out.

Lactation

Contraindicated or not

Storage

Inj Store Below 40°C. Do not Freeze. Protect from Sunlight. Tab Store in a well closed container, Below 40°C.

Price Intelligence

Rs 1,136.6

Servaid observed price · as of 30 July 2026

No approved ceiling matched to this exact pack and strength.

Prices across sources

ServaidRs 1,136.6

Should you consider an alternative?

Other options containing Neostigmine, and what they are not.

Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.

Glycosting

Rs 614.6

BAJWA

Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.

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Brookes Pharmaceutical Labs (Pvt) Ltd.full profile

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