0.5mg

Nestigin

Nestigin Injection

Neostigmine Methylsulphate

Elite Pharma (Pvt) Ltd

Drug Identity

Active Ingredient

Neostigmine Methylsulphate

Chemical Class

Quaternary Ammonium

Pharmacological Group

on the basis of mechanism of action and also cl...

ATC Code

N07AA01, S01EB06

Status

Essential Medicine

What is Nestigin?

Uses

Neostigmine is used to reverse the effects of anesthesia medications used during surgery . Neostigmine may also be used for purposes not ...

How It Works

Chemical Class

Quaternary Ammonium

Pharmacological Group

on the basis of mechanism of action and also classified in Antidotes and Cholinergic Agonist pharmacological group

Neostigmine (Methylsulphate),are the derivatives of Neostigmine. It is of Synthetic origin and belongs to Quaternary Ammonium. It belongs to Cholinesterase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antidotes and Cholinergic Agonist pharmacological group. The Molecular Weight of Neostigmine is 223.30. It is weakly acidic drug, 4.98% solution of the drug is isotonic and Its pKa is 12.0.

How to Take It

Adult · IM

0.02 mg/ kg — As recommended.

For diagnosis of myasthenia gravis

Adult · IV, IM, SC

0.5 to 2.5 mg — As recommended.

Additional doses depend upon the patient response. Max. 10mg/day

Adult · PO

15 mg — 4 hourly

Max. 375mg/day

Child · Intra Venous

50 to 0 ug/kg — As recommended.

To severe neuromuscular blockade.

Child · Oral

200 to 0 mg/kg — 6 hourly

For Myasthenia grains.

Safety Alerts

You should not be treated with neostigmine if you are allergic to it, or if you have: a bladder obstruction or other urination problems

a blockage in your digestive tract (stomach or intestines)

or a serious disorder called peritonitis (inflammation of the membrane lining the organs inside your abdomen)

Tell your doctor if you have ever had: coronary artery disease (clogged arteries)

a heart rhythm disorder

Important Warnings

You should not be treated with neostigmine if you have a bladder or bowel obstruction , or a serious disorder called peritonitis (inflammation of the membrane lining the organs inside your abdomen)

Side Effects

Get emergency medical help if you have signs of an allergic reaction : hivesdifficult breathingswelling of your facelipstongueor throat. Tell your caregivers right away if you have muscle weakness as you wake up from surgery. Common side effects of neostigmine may include: nauseavomitingor slow heartbeats. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Drug Interactions

Other drugs may affect neostigmine

including prescription and over-the-counter medicines

vitamins

and herbal products . Tell your doctor about all your current medicines and any medicine you start or stop using.

Storage

Inj Store Below 40°C. Do not Freeze. Protect from Sunlight. Tab Store in a well closed container, Below 40°C.

Price Intelligence

Rs 2,059.06

DRAP approved maximum price · per pack of 100 · approved 12 Dec, 2025

No retail price observed for this pack. Retailers may not exceed the approved maximum.

Prices across sources

No retail prices recorded

Should you consider an alternative?

Other options containing Neostigmine Methylsulphate, and what they are not.

Identical active ingredient at the same strength. Cheapest per unit first.

Neostig

0.5mg

Rs 1,079.84

No DRAP alertsSIZA INTERNATIONAL (PVT) LTD.

Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.

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