Drug Identity
Active Ingredient
Naltrexone
Chemical Class
Cyclopropane
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
N07BB04
Status
Essential Medicine
What is Nevitrol?
Uses
Naltrexone is a prescription medication used to treat alcohol use disorder (AUD) and opioid use disorder (OUD) to reduce cravings and hel...
How It Works
Chemical Class
Cyclopropane
Pharmacological Group
on the basis of mechanism of action and also classified in Antidotes pharmacological group
It is of Synthetic origin and belongs to Cyclopropane. It belongs to OPIATE antagonist pharmacological group on the basis of mechanism of action and also classified in Antidotes pharmacological group. The Molecular Weight of Naltrexone is 341.40. Its pKa is 8.13.
How to Take It
1
Adult · PO
50 mg — 24 hourly
Then.
2
Child
Safety not established
Safety Alerts
You should not be treated with this medicine if you are allergic to it, or if: you are currently addicted to opioids
you are having withdrawal symptoms from opioid addiction
you are using any opioid pain medicine (including fentanyl, Vicodin, OxyContin, and many others)
you have failed the naloxone challenge test or have a positive urine screen for opioids or you have used any opioid medicine such as methadone, buprenorphine, tramadol, and other opioids within 7 to 14 days
Also, tell your doctor if you have or have ever had: bleeding problems such as hemophilia
Important Warnings
This medicine can cause serious side effects, including: Risk of opioid overdose
You can accidentally overdose in two ways
Naltrexone blocks the effects of opioid drugs
Do not take large amounts of opioids, including opioid-containing medicines, such as heroin or prescription pain pills, to try to overcome the opioid-blocking effects of this medication
This can lead to serious injury, coma, or death
After you receive a dose of the extended-release injection form of this medication, its blocking effect slowly decreases and completely goes away over time
If you have used opioid street drugs or opioid-containing medicines in the past, using opioids in amounts that you used before treatment can lead to overdose and death
You may also be more sensitive to the effects of lower amounts of opioids: after you have gone through detoxification when your next injection is due if you miss a dose of this medication after you stop treatment with this medicine It is important that you tell your family and the people closest to you of this increased sensitivity to opioids and the risk of overdose
Side Effects
The severe or irreversible adverse effects of Naltrexonewhich give rise to further complications include Hepatic damageThrombocytopenic purpura. The signs and symptoms that are produced after the acute overdosage of Naltrexone include Liver dysfunction. The symptomatic adverse reactions produced by Naltrexone are more or less tolerable and if they become severethey can be treated symptomaticallythese include TirednessHeadacheDiarrheaAnxietyRestlessnessAbdominal crampsSkin rashesGI adverse effectsSomnolenceNausea and vomitingMuscle aching
Drug Interactions
Tell your healthcare provider about all the medicines you take
including prescription and non-prescription medicines
vitamins
and herbal supplements. Especially tell your healthcare provider if you take any opioid-containing medicines for pain
cough or colds
or diarrhea. If you are being treated for alcohol dependence but also use or are addicted to opioid-containing medicines or opioid street drugs
it is important that you tell your healthcare provider before starting naltrexone to avoid having sudden opioid withdrawal symptoms when you start treatment. Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.
Storage
Tab Store Below 40°C. Protect from Sunlight and Heat.
Price Intelligence
Rs 1,232.94
DRAP approved maximum price · per pack of 10 · approved 23 Jul, 2026
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 10Rs 1,232.94
Should you consider an alternative?
Other options containing Naltrexone, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Opinil
50mg
Rs 1,132.17 ceiling
No DRAP alertsHIGHNOON LABORATORIES LTD.
Vivox
50mg
Rs 1,232.94 ceiling
No DRAP alertsGenetics Pharmaceuticals Pvt. Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
181
brands
194
molecules
28
alerts