Drug Identity
Active Ingredient
Ondansetron
Drug Class
Gastro
ATC Code
A04AA01
Status
Essential Medicine
What is Onset?
Uses
Ondansetron (HCl) is oral and parenteral antiemetic agent. Ondansetron (HCl) is the first selective serotonin blocking agent to be market...
How It Works
IM: Should be given undiluted. IV: Give first dose 30 min prior to beginning chemotherapy; the IV preparation has been successful when administered orally. IVPB: Infuse over 15-30 min; 24-hour continuous infusions have been reported, but are rarely used. RECONSTITUTION: Prior to IV infusion, dilute in 50-100 ml D5W or NS.
How to Take It
1
Adult · IV
0.15 to 0.45 mg/ kg — 4 hourly
Max. Dose =32 mg. Give 30 Min. before emetogenic drugs.
2
Adult · PO
8 mg — 8 hourly
Oral treatment is recommended for protection against delayed or prolonged emesis after first 24 hrs. Give upto 5 days.
3
Child · IV Infusion
5 mg/m2 — As recommended.
Initially for 15 Min (Rec. for 5-12 Yrs)
4
Child · Oral
4 mg — 2 hourly
Maintenance for 5 Days
Safety Alerts
Ondansetron (HCl) is contraindicated in conditions like Hypersensitivity
Important Warnings
Hepatic impairment, adenotonsillar surgery, sub acute intestinal obstruction, susceptibility to QT-interval prolongation(including electrolyte disturbances)
Side Effects
Constipationheadacheflushingarrhythmiasbradycardiachest painhiccupshypotensionmovement disordersseizuretransient rise in liver enzymesST segment depressionextra-pyramidal reactionsvisual disturbance.
Drug Interactions
Tramadol
Phenytoin
rifampicin
carbamazepine
Pregnancy & Lactation
Pregnancy
Caution advised
Lactation
Caution advised
Storage
Inj (reconstituted soln) Store at room temperature. Use within 24-48 hrs if kept at room temperature. Tab, Syrup, Suppositories Store at room temperature. Protect from Sunlight.
Price Intelligence
Rs 1,101.13
DRAP approved maximum price · per 4ml · approved 01 Jul, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper 4mlRs 1,101.13
Should you consider an alternative?
Other options containing Ondansetron, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Ondaset
2mg/ml
Rs 220
No DRAP alertsAspin Pharma
Neusetro
2mg/ml
Rs 3,879.25
NEUTRO PHARMA (PVT) LTD.
Dysit
2mg/ml
Rs 4,982.08 ceiling
No DRAP alertsWIMITS
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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