Pine

Pine Injection

Heparin Sodium

Werrick Pharmaceuticals Pakistan

Drug Identity

Active Ingredient
Heparin Sodium
Drug Class
Antithrombotic Agents
ATC Code
B01AB01, C05BA03, S01XA14
Status
Essential Medicine

What is Pine?

Uses
Heparin is an anticoagulant (blood thinner) that prevents the formation of blood clots. Heparin is used to treat and prevent blood clots ...

How It Works

Infuse via infusion pump. Heparin lock: Inject via inj cap using positive pressure flushing technique. Heparin lock flush solution is intended only to maintain potency of IV devices & is not to be used for anticoagulant therapy. Administer SC injection into anterior abdominal wall, above the iliac crest & 5 cm or more away from the umbilicus. To minimize tissue trauma, fill adipose tissue away from deep tissues. Do not move needle while injecting drug & do not massage inj site before or after inj. Apply gentle pressure to the site after withdrawing needle. Use alternate inj sites. Standard diluent: 25000 units/500 ml D5W (premixed). Minimum volume: 250 ml D5W. For continuous inf, to prevent drug from pooling, invert container at least 6 times.

How to Take It

1
Adult · IV
5000 IU — As recommended.
For treatment of deep vein thrombosis.
2
Adult · IV-Inf
15 to 25 IU/kg/hr — As recommended.
followed after IV-inj.
3
Adult · SC
5000 IU — 8 hourly
For prophylaxis of deep vein thrombosis.
4
Adult · Topical
0.3 % — 6 hourly
5
Child · IV Infusion
25 IU/kg.hr — As recommended.
As Required

Safety Alerts

Haemorrhagic, diathesis, deficiency of coagulation factors, severe hepatic, renal or pancreatic impairment, severe thrombocytopenia, GI ulcers, hypertension, brain haemorrhage, COS injury or surgery, cerebral arterial aneurysm, retinopathy, vitreous haemorrhage, ophthalmic surgery, subacute bacterial endocarditis, imminent abortion, spinal or epidural anaesthesia, lumbar puncture, thrombocytopenia (type II) caused by heparin allergy, suspected malignant tumour with risk of bleeding, nephro- and ureterolithiasis, chronic alcohol abuse

Important Warnings

Elderly, thrombocytopenia, organ punctures & angiography, cancer, post-surgical patients, advanced renal or hepatic disease, jaundice, neonates

Side Effects

Bleeding complicationstransient alopeciathrombocytopeniaosteoporosis (long-term therapy)febrileor allergic reactionshypoaldosteronismreaction at injection site.

Drug Interactions

Acetyl salicylic acid
coumarin derivatives
dux-Van
dipyridamole
NSAIDs
fibrinolytics
penicillin (high dose). IV nitroglycerin
propranolol

Pregnancy & Lactation

Pregnancy
Caution advised; maternal osteoporosis reported after prolonged use
Lactation
May be used in breast feeding

Storage

Inj Store at room temperature, Between 15°C-25°C. Do not Freeze. Protect from Sunlight.

Price Intelligence

Rs 580.7
Servaid observed price · as of 30 July 2026
DRAP approved ceiling: Rs 1,556.51 (per 5ml)
Pack size is not recorded for both figures, so we do not compare them here.
Reg. 031375 · approved 22 Jul, 2026
Prices across sources
ServaidRs 580.7
DRAPper 5mlRs 1,556.51

Should you consider an alternative?

Other options containing Heparin Sodium, and what they are not.

These contain this ingredient plus others. They are different medicines — do not swap.

Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.

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Company

Prices as of 30 July 2026 · DRAP ceiling as of 30 July 2026 · schema v3-SKU

For medicine intelligence and professional reference only. Not medical advice.