Drug Identity
Active Ingredient
Propylthiouracil
Drug Class
Thyroid Therapy
Chemical Class
Pyrimidine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
H03BA02
Status
Essential Medicine
What is Procarbizole?
Uses
Propylthiouracil is used to treat hyperthyroidism (overactive thyroid), Graves' disease , or toxic goiter (enlarged thyroid). propylthiou...
How It Works
Chemical Class
Pyrimidine
Pharmacological Group
on the basis of mechanism of action and also classified in Antithyroid pharmacological group
It is of Synthetic origin and belongs to Pyrimidine. It belongs to Thyroid peroxidase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antithyroid pharmacological group. The Molecular Weight of Propylthiouracil is 170.23. Its pKa is 7.5.
How to Take It
1
Adult · PO
0.71 mg/kg — 8 hourly
Maintenance for 18 Months
2
Adult · PO
1.43 to 3.81 mg/kg — 8 hourly
Load for 4-8 Weeks
3
Adult
Scraped Dose
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Propylthi
4
Child · Oral
0.6 to 2 mg/kg — 8 hourly
Dose for Children 5-12 Yrs Age
Safety Alerts
You should not use propylthiouracil if you are allergic to it
Tell your doctor if you have ever had liver problems
In very rare cases, propylthiouracil has caused liver failure and death in pregnant women during the second or third trimester of pregnancy
Tell your doctor if you are pregnant or plan to become pregnant
Tell your doctor if you are breastfeeding
Important Warnings
Renal or hepatic impairment, age above 40, years
Side Effects
Arthralgiafeverheadachejaundiceleucopeniamalaisemild GIdisturbancesnauseapruritusrashtaste disturbance. Rare: Agranulocytosisalopeciaaplastic anaemiabone marrow suppressioncutaneous vasculitis
Drug Interactions
Warfarin
anticoagulants
correction of hyperthyroidism may alter disposition of beta-blockers
digoxin
the-ophylline
Pregnancy & Lactation
Pregnancy
Positive evidence of risk: Use only when no safer alternative exists for a serious problem.
Lactation
Contraindicated or not recommended.
Storage
Tab Store in a well closed container, Below 40°C.
Price Intelligence
Rs 123
Servaid observed price · as of 30 July 2026
Prices across sources
DRAPper pack of 100Rs 219.86
ServaidRs 123
Should you consider an alternative?
Other options containing Propylthiouracil, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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