Drug Identity
Active Ingredient
Quinine Dihydrochloride
Chemical Class
Alkaloid
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
P01BC01
Status
Essential Medicine
What is Quininedihydrochloride?
Uses
The U.S. Food and Drug Administration has banned the sale of all non-approved brands of quinine. Do not purchase quinine on the Internet ...
How It Works
Chemical Class
Alkaloid
Pharmacological Group
on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group
Quinine (Bisulphate) is the derivative of Quinine. It is of Natural origin and belongs to Alkaloid. It belongs to Antiplasmodial pharmacological group on the basis of mechanism of action and also classified in Antimalarial Agent pharmacological group. The Molecular Weight of Quinine is 324.40. It is strongly acidic drug, 5.07% solution of the drug is isotonic and Its pKa is 4.1, 8.5.
How to Take It
1
Adult · PO,IM,IV Inf
10 mg/ kg — 8 hourly
For 7 days.
2
Adult
Scraped Dose
Follow all directions on your prescription label. Do not take quinine in larger or smaller amounts or for longer than recommended. Take with food if quinine upsets your stomach. Take this medicatio
3
Child · Oral
10 mg/kg — 8 hourly
For 7 Days (As Quinine Sulphate)
Safety Alerts
You should not use this medication if you have ever had an allergic reaction to quinine or similar medicines such as mefloquine or quinidine, or if you have: a heart rhythm disorder called Long QT syndrome
an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G-6-PD)
myasthenia gravis
optic neuritis (inflammation of the optic nerve)
or if you have taken quinine in the past and it caused a blood cell disorder, severe bleeding, or kidney problems
Important Warnings
Quinine can cause serious side effects on your heart, kidneys, or blood cells
Stop taking quinine and call your doctor at once if you have headache with chest pain and severe dizziness, fast or pounding heartbeats, unusual bruising or bleeding (nosebleeds, bleeding gums, purple or red spots under your skin), signs of infection (fever, chills, mouth sores), severe lower back pain, or blood in your urine
You should not take quinine if you have a heart rhythm disorder called Long QT syndrome , a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G-6-PD), myasthenia gravis , optic neuritis (inflammation of the nerves in your eyes), if you have taken quinine in the past and it caused a blood cell disorder or severe bleeding
Some people have used quinine to treat leg cramps, but this is not an FDA-approved use
Using this medication improperly or without the advice of a doctor can result in serious side effects or death
Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hivesdifficulty breathingswelling of your facelipstongueor throat. Quinine may cause serious side effects. Call your doctor at once if you have: feverchillsbody achesflu symptomssores in your mouth and throateasy bruisingunusual bleeding (nosemouthvaginaor rectum)
Drug Interactions
Many drugs can interact with quinine. Not all possible interactions are listed here. Tell your doctor about all your medications and any you start or stop using during treatment with quinine
especially: acetazolamide
sodium bicarbonate
aminophylline
theophylline
arsenic trioxide
vandetanib
bosentan
Storage
Tab, Inj Store in a well closed container, Below 40°C.
Price Intelligence
Rs 840.4
DRAP approved maximum price · per pack of 100 · approved 01 Jul, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 100Rs 840.4
Should you consider an alternative?
Other options containing Quinine Dihydrochloride, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Zafquin
300mg
Rs 502.67 ceiling
ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
Zafquin
300mg/ml
Rs 502.67 ceiling
ZAFA PHARMACEUTICAL LABORATORIES (PVT) LTD.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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