Drug Identity
Active Ingredient
Rifampicin
Drug Class
Antimycobacterials (Antituberculosis)
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
J04AB02
Status
Essential Medicine
What is RIFADIN?
Uses
Rifampicin belongs to the group of complex macrocyclic antibiotic. Rifampicin is a zwitterionic. Rifampicin results from a condensation r...
How It Works
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group
Rifampicin also known as Rifampin. It is of Synthetic origin and belongs to Rifamycin. It belongs to rRNA polymerase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group. The Molecular Weight of Rifampicin is 822.90. Its pKa is 1.7, 7.9.
How to Take It
1
Adult · PO
450 to 600 mg — As recommended.
In 2-4 div.doses. Maximum dose: 600mg. Give 30 min before breakfast. Duration may vary according to indication.
2
Child · Oral
10 to 20 mg/kg — 24 hourly
Max 60mg/day
Safety Alerts
Previous hypersensitivity to any rifamycin, Acute porphyrias, jaundice
Important Warnings
Caution patients against intentional or accidental interruption of daily dosage regimen for renal hypersensitivity reactions when therapy is resumed
Urine, faeces, saliva, sputum, sweat and tears may be coloured red-orange
Side Effects
Acute renal failureadrenal insufficiencyalterations of liver functionanorexiaantibiotic-associated colitisbody secretions coloured orange-redcollapse and shockdiarrhoeadisseminated intravascular coagulationDrowsinesseosinophiliaexfoliative dermatitisflushingGI symptomshaemolytic anaemia
Drug Interactions
Rifampicin induces hepatic enzymes which accelerate the metabolism of several drugs including oestrogens
corticosteroids
phenytoin
sulfonylureas
and
Pregnancy & Lactation
Pregnancy
Caution advised, use only if potential benefit outweighs risk
Lactation
Caution advised
Storage
Inj (reconstituted soln) Store at room temperature. Use within 24 hrs if kept at room temperature. Tab, Caps, Susp Store in a well closed container, Below 40°C. Protect from Sunlight, Moisture and Heat.
Price Intelligence
Rs 569.79
DRAP approved maximum price · per pack of 48 · approved 01 Jul, 2024
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper 60mlRs 108.08
Should you consider an alternative?
Other options containing Rifampicin, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Unerif
300mg
Rs 17.09
No DRAP alertsUNEXO LABS (PVT) LTD.
Rimso
300mg
Rs 43.33 ceiling
HILTON PHARMA (PVT) LIMITED
Rimpin
300mg
Rs 500.36 ceiling
WERRICK PHARMACEUTICALS
Rimactal
300mg
Rs 91.8
Below approved ceilingGlobal Pharmaceuticals Pvt Ltd
Rifapin
300mg
Rs 6.65 ceiling
No DRAP alertsSchazoo Zaka (Pvt) Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
172
brands
167
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