Drug Identity
Active Ingredient
Pyrazinamide
Chemical Class
Amidopyrazine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
J04AK01
Status
Essential Medicine
What is Rifater?
Uses
Pyrazinamide is an antibiotic that fights bacteria. Pyrazinamide is used to treat tuberculosis (TB) in adults and children. Pyrazinamide ...
How It Works
Chemical Class
Amidopyrazine
Pharmacological Group
on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group
It is of Synthetic origin and belongs to Amidopyrazine. It belongs to Antimycobacterial agent pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group. The Molecular Weight of Pyrazinamide is 123.10. Its pKa is 0.5.
How to Take It
1
Adult · PO
20 to 35 mg/ kg — As recommended.
Daily in 3-4 div.doses. Maximum dose: 3 g/24hr. Usually given during 1st 2 months of therapy.
2
Adult
Scraped Dose
Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for l
3
Child · Oral
5 mg/kg — 6 hourly
For Paeds of All Ages
Safety Alerts
You should not use pyrazinamide if you are allergic to it, or if you have: active gout
or severe liver disease
To make sure pyrazinamide is safe for you, tell your doctor if you have: HIV or AIDS
or if you drink large amounts of alcohol
Your doctor will check your liver enzymes and uric acid levels before you start treatment, to make sure you can safely take pyrazinamide
Important Warnings
You should not use pyrazinamide if you have active gout or severe liver disease
Side Effects
Get emergency medical help if you have signs of an allergic reaction: hivesdifficult breathingswelling of your facelipstongueor throat. Pyrazinamide may cause serious side effects. Call your doctor at once if you have: feverjoint pain or swellingeasy bruising or bleeding (nosebleedsbleeding gums)gout flare-up symptoms --joint painstiffnessrednessor swelling (especially at night)or liver problems -- nauseaupper stomach pain
Drug Interactions
Other drugs may interact with pyrazinamide
including prescription and over-the-counter medicines
vitamins
and herbal products . Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Storage
Tab Store Below 40°C. Protect from Moisture and Heat.
Price Intelligence
Rs 605.1
DRAP approved maximum price · per pack of 60 · approved 01 Jul, 2024
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 60Rs 605.1
Should you consider an alternative?
Other options containing Pyrazinamide, and what they are not.
Same active ingredient, a different dose. Never switch strength without your doctor or pharmacist.
Rifazol +
400mg
Rs 1,068.8 ceiling
No DRAP alertsSchazoo Zaka (Pvt) Ltd
Pyratar
60mg
Rs 8.36 ceiling
No DRAP alertsUNEXO LABS (PVT) LTD.
Rifin P
50mg
Rs 582.51 ceiling
Pacific Pharmaceutical Ltd
Rifinp
400mg
Rs 582.51 ceiling
Pacific Pharmaceutical Ltd
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
For pharma professionalsCompany, market and opportunity intelligence
Company
172
brands
167
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1
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