Drug Identity
Active Ingredient
Rifampicin
Drug Class
Antimycobacterials (Antituberculosis)
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
J04AC01
Status
Essential Medicine
What is Rimactal INH?
Uses
Rifampicin belongs to the group of complex macrocyclic antibiotic. Rifampicin is a zwitterionic. Rifampicin results from a condensation r...
How It Works
Chemical Class
Rifamycin
Pharmacological Group
on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group
Rifampicin also known as Rifampin. It is of Synthetic origin and belongs to Rifamycin. It belongs to rRNA polymerase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antituberculous Drugs pharmacological group. The Molecular Weight of Rifampicin is 822.90. Its pKa is 1.7, 7.9.
How to Take It
1
Adult · PO
450 to 600 mg — As recommended.
In 2-4 div.doses. Maximum dose: 600mg. Give 30 min before breakfast. Duration may vary according to indication.
2
Child · Oral
10 to 20 mg/kg — 24 hourly
Max 60mg/day
Safety Alerts
Previous hypersensitivity to any rifamycin, patients with previous isoniazid associated hepatic injury or other severe adverse reactions with isoniazid
Important Warnings
Patients with active chronic liver disease or severe renal dysfunction
Isoniazid crosses the placental barrier and passes into maternal breast milk, observe neonates, breast fed infants of isoniazid treated mothers for any evidence of adverse effects, caution patients against intentional or accidental interruption of daily dosage regimen, since rare renal hypersensitivity reactions have been reported when therapy is resumed
Urine, faeces, saliva, sputum, sweat and tears may be coloured red-orange
Side Effects
Anaphylactoid reactionsheartburnepigastric dis-tressanorexianauseavomitingdiarrhoeasore mouthrashpruritusurticariaeosinophiliathrombocytopeniamuscular weaknesspain in extremities
Drug Interactions
Rifampicin induces hepatic microsomal enzymes that metabolize a wide variety of drugs e.g. metoprolol
propranolol
quinidine
corticosteroids
contraceptives
oral anticoagulants
oral sulfonylureas. The effectiveness of isoniazid may be decreased when administered with corticosteroid. The effects of benzodiazepines may be increased. The hepatic toxicity of both isoniazid and/or rifampicin may be increased when administered concomitantly.
Pregnancy & Lactation
Pregnancy
Caution advised, use only if potential benefit outweighs risk
Lactation
Caution advised
Storage
Inj (reconstituted soln) Store at room temperature. Use within 24 hrs if kept at room temperature. Tab, Caps, Susp Store in a well closed container, Below 40°C. Protect from Sunlight, Moisture and Heat.
Price Intelligence
Rs 45.6
DVAGO observed price · as of 30 July 2026
Prices across sources
DVAGORs 45.6
DRAPper pack of 30Rs 488.68
Should you consider an alternative?
Other options containing Rifampicin, and what they are not.
Identical active ingredient at the same strength. Cheapest per unit first.
Rimazid
300mg
Rs 254.53 ceiling
CIBEX (PRIVATE) LIMITED
Rifampicin
300mg
Rs 65.82 ceiling
M/s. Zafa Pharmaceutical Laboratories (Pvt) Ltd
Pire2
300mg
Rs 2,635.63 ceiling
No DRAP alertsM/s. Genix Pharma (Pvt) Ltd.
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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