Drug Identity
Active Ingredient
Cyclosporin
Drug Class
General
Chemical Class
Polypeptide
Pharmacological Group
on the basis of mechanism of action and also cl...
What is Sandimmun Neoral?
Uses
Cyclosporine weakens your body's immune system, to help keep it from "rejecting" a transplanted organ such as a kidney. Organ rejection h...
How It Works
Chemical Class
Polypeptide
Pharmacological Group
on the basis of mechanism of action and also classified in Antidotes and Immunosuppressant Agent pharmacological group
Cyclosporine A also known as Ciclosporin. It is of Natural origin and belongs to Polypeptide. It belongs to Immune Modifiers pharmacological group on the basis of mechanism of action and also classified in Antidotes and Immunosuppressant Agent pharmacological group. The Molecular Weight of Cyclosporine A is 1202.00. Its pKa is unionized.
How to Take It
1
Adult · PO
150 to 500 mg — 24 hourly
Maintenance
2
Adult · PO
500 to 1000 mg — As recommended.
For once, prior to Transplantation
3
Child · Oral
2.5 to 0 mg/kg — 12 hourly
Post operative for 1-2 Weeks
4
Child · Oral
3 to 10 mg/kg — 24 hourly
Maintenance ,as required
5
Child · Oral
14 to 18 mg/kg — As recommended.
For Once prior to Transplantation
Safety Alerts
You should not use cyclosporine if you are allergic to it
You may not be able to use cyclosporine if you have: kidney disease
untreated or uncontrolled high blood pressure
or any type of cancer
If you are being treated for psoriasis, you should not receive ultraviolet light therapy (PUVA or UVB), radiation treatments, coal tar , or drugs that weaken the immune system (such as methotrexate ) while you are receiving cyclosporine
Important Warnings
You may not be able to use cyclosporine if you have certain medical conditions or are using certain medicines or receiving phototherapy or radiation treatments
MAKE SURE ALL DOCTORS INVOLVED IN YOUR CARE KNOW YOU ARE USING CYCLOSPORINE
Cyclosporine may increase your risk of developing serious infections, cancer, or transplant failure
Talk with your doctor about the risks and benefits of using this medication
Side Effects
Get emergency medical help if you have signs of an allergic reaction : hivesdifficult breathingswelling of your facelipstongueor throat. Cyclosporine may cause serious side effects. Call your doctor at once if you have: problems with speechthoughtvisionor muscle movement (may start gradually and get worse quickly)a seizuresevere headacheblurred visionpounding in your neck or earspale skineasy bruising
Drug Interactions
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take
which may increase side effects or make the medications less effective. Cyclosporine can harm your kidneys
especially if you also use certain medicines for infections
cancer
osteoporosis
organ transplant rejection
bowel disorders
high blood pressure
Storage
Caps Store in a well closed container, Below 25°C. Soln Store in a well closed container, Below 25°C. Refrigeration and Freezing is not recommended.
Price Intelligence
Rs 7,152.42
DRAP approved maximum price · per pack of 50 · approved 01 Jul, 2024
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 50Rs 7,152.42
Should you consider an alternative?
Other options containing Cyclosporin, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Ristasesopthalmicemulsion
10ml
Rs 292.22
SANTE (PVT) LIMITED
Cycloscot
100mg/5ml
Rs 1,319.75
No DRAP alertsSCOTMANN PHARMACEUTICALS
Bioral
25mg
Rs 1,940
Below approved ceilingNo DRAP alertsALLMED LABORATORIES
Cipoln
25mg
Rs 2,231
No DRAP alertsHOFFMAN HEALTH PAKISTAN LTD.
Bioral
50mg
Rs 3,881
Below approved ceilingNo DRAP alertsALLMED LABORATORIES
Cipoln
50mg
Rs 4,463
No DRAP alertsHOFFMAN HEALTH PAKISTAN LTD.
Sandimmun
250mg
Rs 5,164.6
Below approved ceilingNOVARTIS
Bioral
100mg
Rs 7,756
Below approved ceilingNo DRAP alertsALLMED LABORATORIES
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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