Drug Identity
Active Ingredient
Levodopa
Drug Class
Anti-Parkinson Drugs
Chemical Class
Phenyl Alanine
Pharmacological Group
on the basis of mechanism of action and also cl...
ATC Code
N04BA01
Status
Essential Medicine
What is Sinedopa?
Uses
Levodopa inhalation is used to treat symptoms of Parkinson's disease that come back (OFF episodes) while you are taking another medicine ...
How It Works
Chemical Class
Phenyl Alanine
Pharmacological Group
on the basis of mechanism of action and also classified in Antiparkinson Agents pharmacological group
Levodopa also known as L-dopa. It is of Natural origin and belongs to Phenyl Alanine. It belongs to Dopamine agonist pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents pharmacological group. The Molecular Weight of Levodopa is 197.20. Its pKa is 2.3, 8.7,9.7, 13.4.
How to Take It
1
Adult · PO
100 mg — 8 hourly
Initial, With carbidopa 25 mg, increase gradually as required .
2
Adult · PO
750 to 2000 mg — 24 hourly
In div.doses, with carbidopa 75-100 mg, maintenance as required.
3
Child
Safety not established
Safety Alerts
Severe psychosis, narrow angle glaucoma, history of malignant melanoma
Important Warnings
Hepatic and renal impairment, history of convulsions, history of myocardial infarction with residual arrhythmia, Cushing syndrome, diabetes mellitus, endocrine disorders, history ofpeptic ulcer, hyperthyroidism, osteomalacia, phaeochromocytoma, psychiatric illness, severe cardiovascular disease, severe pulmonary disease, susceptibility to angle-closure glaucoma
Monitor blood values, hepatic, renal and cardiovascular function
When cocareldopais used, the total daily dose of carbidopa should be at least 70 mg
A lower dose may not achieve full inhibition of extra cerebraldopa- decarboxylase, with a resultant increase in side-effects
Side Effects
Anorexiaanxietyataxiaarrhythmiasabnormal dreamschoreaconfusiondementiadepressiondizzinessdrowsinessdry mouthdyskinesiadystoniaeuphoria
Drug Interactions
Drugs affecting central amines. MAOls. Antihypertensives and sympathomimetics
ferrous sulphate.
Pregnancy & Lactation
Pregnancy
Use with caution; risk of toxicity
Lactation
Contraindicated
Storage
Tab, Caps Store Below 40°C. Protect from Sunlight and Moisture.
Price Intelligence
Rs 529.97
DRAP approved maximum price · per pack of 30 · approved 22 Aug, 2025
No retail price observed for this pack. Retailers may not exceed the approved maximum.
Prices across sources
DRAPper pack of 30Rs 529.97
Should you consider an alternative?
Other options containing Levodopa, and what they are not.
These contain this ingredient plus others. They are different medicines — do not swap.
Neudopa
275mg
+ Carbidopa
Rs 149.5Rs 14.95/unit
PLATINUM PHARMACEUTICAL
Sinemet
25Mg 250Mg
+ Carbidopa
Rs 269.3Rs 26.93/unit
OBS Pakistan Pvt. Ltd
SINEMET
25mg
+ Carbidopa
Rs 283.52
Below approved ceilingSearle Pakistan Limited
Sinemet Extra
100Mg
+ Carbidopa
Rs 479.1Rs 15.97/unit
Below approved ceilingOBS Pakistan Pvt. Ltd
Aptidopa
25mg
+ Carbidopa
Rs 1,407.73
No DRAP alertsAptcure (PVT.) Ltd
Sinemet
250mg
+ Carbidopa
Rs 1,837
Below approved ceilingSearle Pakistan Limited
Lecar
250mg
+ Carbidopa
Rs 1,477.27 ceiling
No DRAP alertsNAVEGAL LABORATORIES
Sinemet Extra
25mg
+ Carbidopa
Rs 529.24 ceiling
Searle Pakistan Limited
Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.
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