SINEMET

Sinemet

SINEMET

Carbidopa

SEARLE PAKISTAN (PVT.) LTD.

Drug Identity

Active Ingredient
Carbidopa
Drug Class
Neuro
Chemical Class
Propionic Acid
Pharmacological Group
on the basis of mechanism of action and also cl...
0

What is Sinemet?

Uses
Carbidopa is used with another medicine called levodopa to treat symptoms of Parkinson's disease , such as stiffness or tremors. Carbidop...

How It Works

Chemical Class
Propionic Acid
Pharmacological Group
on the basis of mechanism of action and also classified in Antiparkinson Agents pharmacological group

Carbidopa also known as Methyldopa hydrazine. It is of Synthetic origin and belongs to Propionic Acid. It belongs to L-amino acid decarboxylase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antiparkinson Agents pharmacological group.The Molecular Weight of Carbidopa is 226.25. Its pKa is 2.3, 7.3.

How to Take It

1
Adult · PO
25 mg — 8 hourly
Initially with levodopa 100 mg.
2
Adult · PO
75 to 100 mg — 24 hourly
Maintenance in div.doses, With levodopa750 2000 mg,
3
Adult
Scraped Dose
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. If you al
4
Child
Not recommended in this age group

Safety Alerts

Severe psychosis, narrow angle glaucoma, history of malignant melanoma

Important Warnings

Hepatic and renal impairment, history of convulsions, history of myocardial infarction with residual arrhythmia, Cushing syndrome, diabetes mellitus, endocrine disorders, history ofpeptic ulcer, hyperthyroidism, osteomalacia, phaeochromocytoma, psychiatric illness, severe cardiovascular disease, severe pulmonary disease, susceptibility to angle-closure glaucoma
Monitor blood values, hepatic, renal and cardiovascular function
When cocareldopais used, the total daily dose of carbidopa should be at least 70 mg
A lower dose may not achieve full inhibition of extra cerebraldopa- decarboxylase, with a resultant increase in side-effects

Side Effects

Anorexiaanxietyataxiaarrhythmiasabnormal dreamschoreaconfusiondementiadepressiondizzinessdrowsinessdry mouthdyskinesiadystoniaeuphoria

Drug Interactions

Drugs affecting central amines. MAOls. Antihypertensives and sympathomimetics
ferrous sulphate.

Pregnancy & Lactation

Pregnancy
Use with caution; risk of toxicity
Lactation
Contraindicated

Storage

Tab Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.

Price Intelligence

Rs 1,837
Servaid observed price · as of 30 July 2026
DRAP approved ceiling: Rs 2,975.23 (per pack of 100)
Pack size is not recorded for both figures, so we do not compare them here.
Reg. 003627 · approved 22 Jul, 2026
Prices across sources
ServaidRs 1,837
DRAPper pack of 100Rs 2,975.23

Should you consider an alternative?

Other options containing Carbidopa, and what they are not.

Identical active ingredient at the same strength. Cheapest per unit first.

Ordered by lowest price per unit where a pack size is known, then by price. Order is never affected by sponsorship. Not medical advice — confirm any change with your pharmacist or doctor.

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Prices as of 30 July 2026 · DRAP ceiling as of 30 July 2026 · schema v3-SKU

For medicine intelligence and professional reference only. Not medical advice.